PMID: 9184285Jun 1, 1997Paper

Progression of atherosclerosis after venous coronary artery bypass graft surgery: a 15-year follow-up study

Catheterization and Cardiovascular Diagnosis
B L van BrusselH C Kelder

Abstract

We investigated the influence of progression of atherosclerosis on clinical outcome in a cohort of 428 consecutive patients with isolated venous coronary artery bypass graft surgery followed prospectively for 15 years. In 189 patients 307 repeat coronary angiograms were performed because of recurrent signs of ischemia. Progression in the native coronary circulation only was found in 38 angiograms (12%), in both the native circulation and in venous grafts in 66 angiograms (21%), in venous grafts only in 135 angiograms (44%), and no progression was found in 68 angiograms (22%). In all the angiographies with a proven progression in the native coronary arteries, 40% was found to be distal to a vein graft insertion. In multivariate analysis the number of distal anastomoses predicts progression in both the native circulation and in venous grafts. Thus, progression is determined by the extensiveness of coronary artery disease at operation. Also, the interval between operation and repeat angiography predicts progression in the native circulation. We conclude that clinical outcome is also determined by progression in the native coronary circulation. Secondary prevention may, therefore, benefit not only the long-term result in patients w...Continue Reading

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Citations

Feb 24, 2006·Journal of Cardiac Surgery·Rohit AroraHarold L Lazar
Apr 29, 1998·The American Journal of Cardiology·A J LanskyM B Leon
Feb 22, 2003·American Heart Journal·Lawrence Liao, David F Kong
Oct 6, 2000·The American Journal of Cardiology·J J PopmaS Kinlay
Jun 1, 1997·Catheterization and Cardiovascular Diagnosis·D A Clark
Mar 31, 2005·European Psychiatry : the Journal of the Association of European Psychiatrists·M Cedereke, A Ojehagen
Apr 26, 2002·European Psychiatry : the Journal of the Association of European Psychiatrists·M CederekeA Ojehagen

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