Progression of hand osteoarthritis over 2 years: a clinical and radiological follow-up study

Annals of the Rheumatic Diseases
S Botha-ScheepersM Kloppenburg

Abstract

To investigate the course of hand osteoarthritis over 2 years by currently available outcome measures. 189 participants of the Genetics, Arthrosis and Progression (GARP) study with hand osteoarthritis were followed for 2 years. Self-reported hand pain and functional limitations were assessed with the Australian/Canadian osteoarthritis hand index (AUSCAN LK 3.0). Pain intensity upon lateral pressure in the interphalangeal and thumb base joints was graded on a four-point scale. Osteophytes (0-3) and joint space narrowing (JSN) (0-3) was scored at baseline and after 2 years in interphalangeal and thumb base joints. Standardised response means (SRM) were calculated. 172 (91%) patients completed the 2-year follow-up (mean age 60.5 years, 78.5% women). Statistically significant increases in self-reported pain and function scores, in pain intensity scores as well as in osteophyte and JSN total scores were seen over 2 years. SRM were 0.25, 0.23, 0.67, 0.34 and 0.35, respectively, for self-reported pain and function scores, pain intensity scores, osteophyte and JSN total scores. Radiological progression was not associated with changes in self-reported pain and function. Women in an early post-menopausal stage were especially at risk of ...Continue Reading

Citations

Feb 22, 2012·BMC Musculoskeletal Disorders·Helgi JonssonVilmundur Gudnason
Feb 18, 2011·European Radiology·Christoph KarloChristian W A Pfirrmann
Sep 14, 2012·Arthritis Care & Research·W Y KwokM Kloppenburg
Jun 2, 2011·Arthritis Care & Research·Ingvild KjekenKåre Birger Hagen
Mar 29, 2014·Annals of the Rheumatic Diseases·Toril HennigIngvild Kjeken
Jan 30, 2013·Osteoarthritis and Cartilage·J BijsterboschI Meulenbelt
Nov 13, 2013·Scandinavian Journal of Occupational Therapy·Merete HermannIngvild Kjeken
Aug 20, 2014·Scandinavian Journal of Occupational Therapy·Ingvild KjekenNina Osterås
Apr 27, 2010·Osteoarthritis and Cartilage·P T ParadowskiM Englund
Sep 20, 2011·Osteoarthritis and Cartilage·W Y KwokM Kloppenburg
Aug 5, 2014·Rheumatology International·Angel Soto-HermidaIgnacio Rego-Pérez
Apr 9, 2017·Annals of the Rheumatic Diseases·Garifallia SakellariouAnnamaria Iagnocco
Jan 25, 2019·Orthopaedic Nursing·Mabel Qi He LeowShian Chao Tay
Nov 23, 2011·Nature Reviews. Rheumatology·Margreet Kloppenburg, Wing-Yee Kwok
Aug 25, 2020·Advances in Rheumatology·Nurhan GüvenSerdar Can Güven
Dec 17, 2018·The Journal of Rheumatology·Féline P B KroonMargreet Kloppenburg
Oct 12, 2018·Nature Reviews. Rheumatology·Michelle MarshallKrysia Dziedzic
Sep 29, 2019·Journal of Clinical Medicine·Anna BenderJuergen Steinmeyer
Oct 23, 2020·Arthritis Care & Research·Lotte A van de StadtMargreet Kloppenburg
May 10, 2018·Deutsches Ärzteblatt International·Christian Karl SpiesFrank Unglaub
Feb 18, 2021·BMC Musculoskeletal Disorders·Ingvild KjekenBarbara Slatkowsky-Christensen
Jun 23, 2020·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Jennifer O'NeilMarie Deanna Westby
Jun 20, 2020·Arthritis Care & Research·Sjoerd van BeestFéline P B Kroon

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