Progression through the RNA polymerase II CTD cycle.

Molecular Cell
Stephen Buratowski

Abstract

The C-terminal domain of RNA polymerase II's largest subunit undergoes dynamic phosphorylation during transcription, and the different phosphorylation patterns that predominate at each stage of transcription recruit the appropriate set of mRNA-processing and histone-modifying factors. Recent papers help to explain how the changes in CTD phosphorylation pattern are linked to the progression from initiation through elongation to termination.

References

Oct 6, 2000·Genes & Development·S C SchroederD Bentley
Jun 7, 2002·Molecular Cell·Donny D LicatalosiDavid L Bentley
Feb 18, 2004·Molecular Cell·Stephanie C SchroederDavid Bentley
Mar 30, 2004·The Journal of Biological Chemistry·Janice C JonesArno L Greenleaf
May 6, 2004·Molecular Cell·Shankarling KrishnamurthyMichael Hampsey
Jun 11, 2004·Eukaryotic Cell·John W Stiller, Matthew S Cook
Aug 4, 2006·Molecular Cell·B Matija Peterlin, David H Price
Dec 13, 2006·Molecular Cell·Minkyu KimStephen Buratowski
Dec 13, 2006·Molecular Cell·Eric J SteinmetzDavid A Brow
Jan 20, 2007·Genes & Development·Sunnie M YohKatherine A Jones
Mar 23, 2007·The Journal of Biological Chemistry·T Max M Søgaard, Jesper Q Svejstrup
May 20, 2008·Cell·Thanasis Margaritis, Frank C P Holstege
Jul 29, 2008·Nature Structural & Molecular Biology·Lidia VasiljevaAnton Meinhart
Jul 29, 2008·Nature Structural & Molecular Biology·Rajani Kanth GudipatiDomenico Libri
Dec 6, 2008·Science·Pascal PrekerTorben Heick Jensen
Jan 10, 2009·The EMBO Journal·Seong Hoon AhnStephen Buratowski
Feb 3, 2009·Nature Genetics·Paulina Kolasinska-ZwierzJulie Ahringer
Feb 20, 2009·Nature·Piero Carninci
Feb 26, 2009·Nature Genetics·Robert J Sims, Danny Reinberg
Apr 15, 2009·Proceedings of the National Academy of Sciences of the United States of America·Karen ZhouJack F Greenblatt
May 20, 2009·Molecular Cell·Md Sohail AkhtarAseem Z Ansari
May 20, 2009·Molecular and Cellular Biology·Sylvain EgloffShona Murphy
Aug 15, 2009·The Journal of Biological Chemistry·Minkyu KimStephen Buratowski
Oct 13, 2009·Molecular Cell·Ana G RondónNick J Proudfoot

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Citations

Mar 13, 2012·Inflammatory Bowel Diseases·Melania Scarpa, Eleni Stylianou
Nov 17, 2010·Chromosoma·Petra Björk, Lars Wieslander
Aug 14, 2013·Journal of Biosciences·Satarupa Das, Biswadip Das
Aug 6, 2013·Trends in Plant Science·Mohsen HajheidariDirk Eick
Apr 20, 2013·Chemical Reviews·Argyris Papantonis, Peter R Cook
Jun 5, 2013·Chemical Reviews·C A NiñoC Dargemont
Aug 8, 2013·Chemical Reviews·Jiannan Guo, David H Price
Jul 11, 2013·Chemical Reviews·Célia JeronimoFrançois Robert
Jun 26, 2013·Nature Genetics·Tim R MercerJohn A Stamatoyannopoulos
Sep 19, 2012·Nature Reviews. Genetics·Karen Adelman, John T Lis
Apr 14, 2011·Nature Reviews. Molecular Cell Biology·Jason N KuehnerClaire Moore
May 24, 2011·Nature Reviews. Molecular Cell Biology·Evelina Tutucci, Françoise Stutz
May 11, 2012·Nature Reviews. Molecular Cell Biology·Emmanuel Compe, Jean-Marc Egly
Jun 22, 2010·Nature Structural & Molecular Biology·Iván D'Orso, Alan D Frankel
Aug 31, 2010·Nature Structural & Molecular Biology·Joshua R TietjenAseem Z Ansari
Sep 8, 2010·Nature Structural & Molecular Biology·Andreas MayerPatrick Cramer
Jul 19, 2011·Nature Structural & Molecular Biology·Frederic KochJean-Christophe Andrau
Sep 6, 2011·Nature Structural & Molecular Biology·Sandra Bento MartinsMaria Carmo-Fonseca
Jul 16, 2013·Nature Structural & Molecular Biology·Evgenia NtiniTorben Heick Jensen
Aug 5, 2010·Nature Structural & Molecular Biology·Matjaz Barboric, Tina Lenasi
Sep 15, 2010·Proceedings of the National Academy of Sciences of the United States of America·Agda Karina Lucio-EterovicPhillip B Carpenter
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Benjamin G KuryanMichael Carey
Apr 18, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ballachanda N DevaiahDinah S Singer
Jun 13, 2012·Proceedings of the National Academy of Sciences of the United States of America·Pierre ChymkowitchJorrit M Enserink
Oct 17, 2012·Proceedings of the National Academy of Sciences of the United States of America·Beate SchwerStewart Shuman
Dec 20, 2012·Proceedings of the National Academy of Sciences of the United States of America·Seemay ChouTom Alber
Aug 20, 2010·The Journal of Biological Chemistry·Man-Hee SuhJianhua Fu
Oct 12, 2010·The Journal of Biological Chemistry·Marie-Laure DieboldChristophe Romier
Oct 1, 2010·The Journal of Biological Chemistry·Khiem Tran, Jay D Gralla
Sep 24, 2011·The Journal of Biological Chemistry·Iwona KarkusiewiczMagdalena Boguta
Aug 23, 2011·The Journal of Biological Chemistry·April L MacKellar, Arno L Greenleaf
Sep 14, 2012·Molecular Biology of the Cell·Alicia GarcíaOlga Calvo
Feb 12, 2011·Nucleic Acids Research·Sílvia Pérez-LluchMontserrat Corominas
Dec 14, 2011·Nucleic Acids Research·Marco A Mendoza-ParraHinrich Gronemeyer
Oct 16, 2012·Nucleic Acids Research·Tomas SikorskyRichard Stefl

❮ Previous
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