Progressive arterial wall stiffening in patients with increasing diastolic blood pressure

Journal of Human Hypertension
F W van den BerkmortelT Thien

Abstract

Hypertension is an established risk factor for cardiovascular disease. Risk factor patterns for various cardiovascular complications are different. We studied the relationship between increasing diastolic blood pressure and arterial wall dynamics of various peripheral arteries in hypertensives to increase insight in the variability of properties within the arterial tree. Eighty-six untreated hypertensives participated in this cross-sectional study. The study-population was divided into quartiles with increasing diastolic office blood pressure. Cross-sectional compliance and distensibility coefficients of the carotid and femoral arteries were determined, using a vessel wall movement detector system (Wall Track System). Diameters of both common carotid arteries enlarged (right: from 7.4 +/- 0.2 to 7.9 +/- 0.2 mm) while cross-sectional compliance (right: from 0.61 +/- 0.04 to 0.42 +/- 0.04 mm(2)/kPa) and distensibility coefficients (right: from 14.2 +/- 1.0 to 9.0 +/- 1.0 10(-3)/kPa) gradually dropped with increasing diastolic blood pressure. Cross-sectional compliance and diameter of the right common femoral artery remained unchanged while distensibility coefficient decreased although less gradually when compared with the carotid...Continue Reading

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Citations

Nov 28, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Michinobu NagaoJunpei Ikezoe
Mar 31, 2009·Clinical and Experimental Hypertension : CHE·Vasileios F PanoulasGeorge D Kitas
Aug 31, 2010·Ultrasound in Medicine & Biology·Mathieu CouadeMickael Tanter
Oct 3, 2015·Journal of Hypertension·Jelle BossuytUNKNOWN Reference Values for Arterial Measurements Collaboration
Jun 14, 2017·Physics in Medicine and Biology·Ali Vaziri AstanehMurthy N Guddati
May 3, 2015·Physiology·Victoria H J RobertsKevin L Grove

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