PMID: 2112620Mar 1, 1990Paper

Progressive bone loss during long-term home total parenteral nutrition

JPEN. Journal of Parenteral and Enteral Nutrition
J FoldesH R Freund

Abstract

Metabolic bone disease occurs in patients receiving prolonged home total parenteral nutrition (HTPN). We studied bone-mass status in 10 patients (seven males, three females, age 19-66 years) who had been receiving HTPN for 0 to 67 months (mean 24 months), mostly for short-bowel syndrome. Four patients had spinal osteoporosis on radiograms. The density of various bone components at the wrist was measured noninvasively using a novel technique based on Compton scattering effect. The density of the cancellous and cortical bone was decreased in nine and six patients, respectively. During a follow-up period of up to 19 months, a further significant decrease in the density of both bone components was found. We conclude that prolonged HTPN is associated with an ongoing bone diminution, affecting mainly the cancellous bone.

Citations

Jan 16, 2007·Langenbeck's Archives of Surgery·Eduardo E Montalvo-JaveMichael G Sarr
Mar 24, 2007·Digestive Diseases and Sciences·Mark DeLeggeNicole M Moore
Dec 4, 2003·Best Practice & Research. Clinical Gastroenterology·Jon A Vanderhoof, Rosemary J Young
Dec 4, 2003·Best Practice & Research. Clinical Gastroenterology·Jeremy Mark Darby Nightingale
Aug 1, 1996·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·L PironiM Miglioli
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Nov 24, 2004·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Loris PironiUNKNOWN ESPEN-home artificial nutrition working group
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Feb 14, 2012·JPEN. Journal of Parenteral and Enteral Nutrition·G FernandesJ P Allard
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Dec 12, 2019·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·P J Allan, S Lal
Mar 23, 2013·Journal of Pediatric Gastroenterology and Nutrition·Stephanie S ApplemanJames E Heubi
Feb 13, 2020·JPEN. Journal of Parenteral and Enteral Nutrition·Luciana T Parreiras-E-SilvaFrancisco José Albuquerque de Paula
Jun 1, 1992·Scottish Medical Journal·C R Pennington

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