Progressive congenital kyphosis: report of five cases and review of the literature

Pediatric Neurosurgery
M F PhilipsL N Sutton

Abstract

For over 60 years congenital kyphotic deformities of the spine have been categorized into two distinct groups, depending on the developmental defect. Those arising from a failure of formation of the vertebral bodies were classified as type 1, while those arising from a failure of segmentation were referred to as type 2. Recognition of the progressive and unstable nature of the type 1 defects alerted physicians to the need for early operative stabilization through decompression and stabilization through instrumentation. As the embryogenesis of the spinal column was further investigated, and as diagnostic imaging methods of the spine improved, unstable congenital kyphoses were further subdivided. Progressive congenital kyphotic deformities now may accompany a host of vertebral column developmental defects as well as genetically mediated mesenchymal tissue defect syndromes. This paper presents 5 patients from The Children's Hospital of Philadelphia with progressive and symptomatic congenital kyphotic deformities of the spine. Two of these lesions resulted from defects of formation of the vertebral bodies, while one resulted from segmental spinal dysgenesis, maldevelopment of both the anterior and posterior vertebral elements. One ...Continue Reading

Citations

Apr 9, 2008·Pediatric Radiology·Anne GeoffrayNancy Béchard-Sevette
Oct 6, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ruth E BristolHarold L Rekate
Jun 24, 2006·Neurologia Medico-chirurgica·Hiroshi NomuraHisaaki Miyahara
Sep 12, 2006·Journal of Neurosurgery. Spine·Mark Chwajol, John K Houten
Aug 28, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·D JeszenszkyT F Fekete
Dec 10, 2014·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·F ForterreC Precht
Mar 5, 2011·Spine·Gérard BolliniJean Dubousset
Nov 19, 2002·Spine·Nitin KhannaLawrence Lenke
Mar 2, 2011·Spine·Kamal Hamoud, Janan Abbas

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