PMID: 16633317Apr 25, 2006Paper

Progressive multifocal leukoencephalopathy secondary to JC virus infection after liver transplantation and treatment of recurrent hepatitis C

Gastroentérologie Clinique Et Biologique
Sophie AlibertDanièle Botta-Fridlund

Abstract

Progressive multifocal leucoencephalopathy due to JC virus is a rare complication of liver transplantation. Only four cases have already been described in the literature. This disease is difficult to differentiate from leucoencephalopathy associated with immunosuppressive drugs such as cyclosporin or tacrolimus. Positive diagnosis of progressive multifocal leucoencephalopathy no longer requires cerebral biopsy. It must be confirmed by positive JC virus RNA amplification in the cerebrospinal fluid. We report a case of progressive multifocal leucoencephalopathy occurring 18 months after liver transplantation for hepatitis C-related cirrhosis.

References

Apr 27, 1994·Transplantation·F WorthmannG Stoltenburg-Didinger
Nov 1, 1995·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·D J BronsterC M Miller
Dec 12, 2001·Journal of Hepatology·J R Boulton-JonesS D Ryder

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Citations

Oct 17, 2009·Medicina clínica·Jaume CampdelacreuTomás Pumarola
May 30, 2019·Journal of Neurovirology·Zahra AhmadinejadFereshteh Ghiasvand
Dec 8, 2010·Transplant International : Official Journal of the European Society for Organ Transplantation·Xavier VerhelstHans Orlent
Aug 9, 2011·Annals of Neurology·Farrah J MateenAvindra Nath
May 26, 2016·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J DumortierO Boillot

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