Projection of mesothelioma mortality in Britain using Bayesian methods.

British Journal of Cancer
E TanJ T Hodgson

Abstract

Mesothelioma mortality has increased more than ten-fold over the past 40 years in Great Britain, with >1700 male deaths recorded in the British mesothelioma register in 2006. Annual mesothelioma deaths now account for >1% of all cancer deaths. A Poisson regression model based on a previous work by Hodgson et al has been fitted, which has allowed informed statistical inferences about model parameters and predictions of future mesothelioma mortality to be made. In the Poisson regression model, the mesothelioma risk of an individual depends on the average collective asbestos dose for the individual in a given year and an age-specific exposure potential. The model has been fitted to the data within a Bayesian framework using the Metropolis-Hastings algorithm, a Markov Chain Monte Carlo technique, providing credible intervals for model parameters as well as prediction intervals for the number of future cases of mortality. Males were most likely to have been exposed to asbestos between the ages of 30 and 49 years, with the peak year of asbestos exposure estimated to be 1963. The estimated number of background cases was 1.08 cases per million population. Mortality among males is predicted to peak at approximately 2040 deaths in the ye...Continue Reading

References

Sep 1, 1996·The European Respiratory Journal·J C McDonald, A D McDonald
Jan 30, 1999·Occupational and Environmental Medicine·A G IlgA J Valleron
Jun 16, 2000·Occupational and Environmental Medicine·A BanaeiS Goldberg
Dec 25, 2002·Occupational and Environmental Medicine·O SeguraC Looman
Sep 12, 2003·International Journal of Occupational and Environmental Health·James Leigh, Tim Driscoll
Jan 26, 2005·British Journal of Cancer·J T HodgsonJ Peto
Apr 24, 2007·Occupational and Environmental Medicine·Mark ClementsAnthony Johnson
Oct 23, 2008·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Mary Jane TetaEdward D Foster

❮ Previous
Next ❯

Citations

Apr 9, 2011·Biomarkers in Medicine·Alfonso CristaudoRudy Foddis
Oct 30, 2015·Occupational Medicine·C M BarberD Fishwick
Jul 12, 2011·The Annals of Occupational Hygiene·Alex Burdorf, Dick Heederik
Apr 13, 2015·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·P BeckettM D Peake
Dec 3, 2017·Clinical Medicine : Journal of the Royal College of Physicians of London·Christopher Jm Whitty
Jun 22, 2012·British Journal of Cancer·Yiqun Chen, John Osman
Jul 14, 2011·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jan P van Meerbeeck, Ronald Damhuis
Jan 23, 2020·International Journal of Environmental Research and Public Health·Enrico OddoneFrancesco Barone-Adesi
Jul 26, 2014·The Oncologist·Jing Ai, James P Stevenson
Mar 18, 2011·Journal of Cellular Physiology·Michele CarboneHaining Yang
Dec 18, 2012·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Vijay AgarwalMichael J Lind
Jan 20, 2016·International Journal of Oncology·Sian CreganSteven G Gray
Jun 18, 2016·Occupational and Environmental Medicine·Carolina MensiDario Consonni
Dec 31, 2015·Occupational and Environmental Medicine·Clare GilhamJulian Peto
Jun 2, 2016·Occupational and Environmental Medicine·María Dolores Martínez-MirandaJens Perch Nielsen
Feb 10, 2016·Occupational and Environmental Medicine·Sjoukje Van der BijHendrik Koffijberg
Feb 16, 2017·International Journal of Oncology·Sian CreganSteven G Gray
May 29, 2013·The Clinical Respiratory Journal·Silvie PrazakovaDeborah H Yates
Jun 8, 2011·International Journal of Cancer. Journal International Du Cancer·Alessandro MarinaccioUNKNOWN ReNaM Working Group
Mar 14, 2019·Frontiers in Endocrinology·Anne-Marie BairdSteven G Gray
May 31, 2013·Deutsches Ärzteblatt International·Volker NeumannAndrea Tannapfel
Aug 15, 2021·Nature Communications·Stefano GrossoAnne E Willis

❮ Previous
Next ❯

Software Mentioned

Matlab

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The British Journal of General Practice : the Journal of the Royal College of General Practitioners
Sarah WalkerWilliam Hamilton
Journal of the History of Medicine and Allied Sciences
Louise Hill Curth
European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
J RehmU Frick
© 2021 Meta ULC. All rights reserved