PMID: 3746682Apr 1, 1986Paper

Projection of pulmonary rapidly adapting receptors to the medulla of the cat: an antidromic mapping study

The Journal of Physiology
R O Davies, L Kubin

Abstract

The activity of pulmonary rapidly adapting receptor (r.a.r.) neurones was recorded extracellularly in the nodose ganglion of the decerebrate cat. The receptors were identified by their rapid adaptation to 'ramp and hold' hyperinflations of the lung. The antidromic mapping technique was used to determine the sites of projection and branching patterns within the nucleus of the tractus solitarius (n.t.s.) of eleven r.a.r.s. The medulla was explored with a stimulating electrode to activate the r.a.r.s. antidromically. In each penetration, depth-threshold measurements were made for each antidromic response characterized by a distinct latency. Using the anatomical sites of the minimum threshold points, the locations of central branches of individual r.a.r.s. were determined. The main axons of all of them coursed within the tractus solitarius (t.s.) at levels from 2 mm rostral to 0.5 mm caudal to the obex. The axonal conduction velocities within the t.s. were 6.2-9.7 m/s, where the peripheral conduction velocities were 11.2-20.4 m/s (28 degrees C). Different latencies of response evoked in a single penetration were considered to indicate branching. The densest branching was found in the ipsilateral commissural subnucleus of the n.t.s....Continue Reading

Citations

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