Prolactin mRNA exists in rat hypothalamus

Endocrinology
B S SchachterB D Shivers

Abstract

Using radiolabeled DNA complementary to rat pituitary prolactin mRNA, we probed RNA gel blots from three rat tissues: pituitary, hypothalamus, and liver. Poly (A)-enriched RNA from male and female hypothalami contained a hybridizable RNA which was the same size as, though less abundant than, mature pituitary PRL mRNA. These results support the proposal that the rat brain synthesizes PRL.

Citations

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Related Concepts

Organum Vasculosum Laminae Terminalis
Genomic Hybridization
Prolactin
August Rats
Poly(A) Tail

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