PMID: 3749730Jan 1, 1986Paper

Proliferation of pannus tissue cells in rheumatoid arthritis

Rheumatology International
W MohrD Wessinghage

Abstract

Proliferation of pannus tissue cells has been investigated under in vitro conditions after labeling of joint tissues with 3H-thymidine. It was demonstrated that there is only a minimal proliferation of chondrocytes as well as of pannus tissue cells. Slight increased proliferation was observed in granulation tissue poor in lymphocytes and plasma cells, and perhaps in those areas of destroying pannus tissue that exhibited polymorphonuclear granulocytes (PMNs) at the pannus-cartilage junction. These results are in contrast to the idea that pannus tissue is a tumor-like lesion, for the present observations, even within the limits of autoradiographic investigations on a heterogeneous tissue, and indicate that pannus tissue has to be regarded as an inflammatory granulation tissue.

References

Jan 1, 1975·Pathologia et microbiologia·W MohrK Paulini
Jun 1, 1975·Annals of the Rheumatic Diseases·W MohrW Mohing
Oct 1, 1985·Arthritis and Rheumatism·D Mitrovic
Aug 1, 1984·Arthritis and Rheumatism·H G Fassbender
Jan 1, 1983·Arthritis and Rheumatism·A E Postlethwaite, A H Kang
Oct 1, 1982·European Journal of Clinical Investigation·D P ParrottG C Fuller
Mar 1, 1983·Collagen and Related Research·H G Fassbender

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Citations

Jun 1, 1995·Annals of the Rheumatic Diseases·R W KinneF Emmrich
May 6, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Birgit GörtzGeorg Schett
Nov 1, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·K A Elsaid, C O Chichester
Apr 23, 2003·The American Journal of Pathology·Christian A SeemayerSteffen Gay
Sep 30, 2016·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Michael J Parnham
Dec 7, 2016·Modern Rheumatology·Jatin SharmaC Subathra Devi
May 8, 2020·Inflammation and Regeneration·Yoko Miura, Satoshi Kanazawa

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