PMID: 765041Feb 1, 1976Paper

Prolonged apnea of prematurity: Treatment with continuous airway distending pressure delivered by nasopharyngeal tube

Clinical Pediatrics
S J Boros, J W Reynolds


Five premature infants experiencing frequent episodes of apnea and bradycardia were treated with continuous positive airway pressure delivered by nasopharyngeal tube. A significant decrease in the frequency and severity of apneic spells was observed. Premature withdrawal from end expiratory pressure resulted in an increase in both the incidence and the duration of the apneic episodes. We suggest that hypoventilation and a reduced functional residual capacity (FRC) are related to the development of prolonged apnea. Expansion and stablization of FRC with small amounts of end expiratory pressure appears to be beneficial.


Jan 1, 1983·Pharmacology & Therapeutics·J V Aranda, L Stern
Aug 12, 2009·Brain & Development·G Terán-PérezJ Velázquez-Moctezuma
Jun 14, 2008·Acta Paediatrica·Tarah T ColaizyJonathan M Klein
Dec 5, 2002·Seminars in Neonatology : SN·Richard A Polin, Rakesh Sahni
Jul 30, 2002·Neonatal Network : NN·S K Berends
Mar 1, 1979·Archives of Disease in Childhood·J L BrazierB L Salle

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