Prolonged extracorporeal membrane oxygenation support for acute respiratory distress syndrome

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Wen-Je KoPi-Ru Tsai

Abstract

When all conventional treatments for respiratory failure in patients with acute respiratory distress syndrome (ARDS) have failed, extracorporeal membrane oxygenation (ECMO) can provide a chance of survival in these desperately ill patients. A 49-year-old male patient developed septic shock and progressive ARDS after liver abscess drainage. Venovenous ECMO was given due to refractory respiratory failure on postoperative day 6. Initially, two heparin-binding hollow-fiber microporous membrane oxygenators in parallel were used in the ECMO circuit. Twenty-two oxygenators were changed in the first 22 days of ECMO support because of plasma leak in the oxygenators. Each oxygenator had an average life of 48 hours. Thereafter, a single silicone membrane oxygenator was used in the ECMO circuit, which did not require change during the remaining 596 hours of ECMO. The patient's tidal volume was only 90 mL in the nadir and less than 300 mL for 26 days during the ECMO course. The patient required ECMO support for 48 days and survived despite complications, including septic shock, ARDS, acute renal failure, drug-induced leukopenia, and multiple internal bleeding. This patient received an unusually long duration of ECMO support. However, he sur...Continue Reading

References

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Oct 13, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Yih-Sharng ChenHsi-Yu Yu
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Citations

Jan 31, 2009·Current Opinion in Critical Care·Antonio PesentiNicolò Patroniti
Nov 26, 2009·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Tsui-Mai KaoShan-Chwen Chang
Aug 5, 2008·Journal of Pediatric Surgery·Taslim F AllibhaiRobert J DiGeronimo
Aug 25, 2015·The Annals of Thoracic Surgery·Zachary N KonBartley P Griffith
Jan 22, 2010·Biotechnology and Bioengineering·Alexa A PolkWilliam R Wagner
Nov 26, 2014·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Kazuhiro KatsuharaTetsuya Matsuoka
Jul 3, 2008·The Annals of Pharmacotherapy·Joel C Marrs
Aug 17, 2018·Prosthetics and Orthotics International·Douglas John MatthewsDavid Ward

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