PMID: 1057785Jul 1, 1975

Prolonged in vitro closure of the mouse secondary palate by salicylates

Scandinavian Journal of Dental Research
I Saxén

Abstract

In organ culture sodium salicylate and acetylsalicylic acid in a 1.4 mM concentration caused prolongation of the time needed for the closure of the mouse secondary palate. The response of Strain A and the hybrids CBA X A was more distinct than that of Strain CBA. The mitotic rate, calculated from serial sections, was significantly reduced in the salicylate-treated shelves in both strains. The extrapolation of the results to an in vivo situation is discussed in the light of different theories of the mechanism of cleft palate formation.

References

Apr 5, 2000·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·M H Rajabian, M Sherkat
Jan 1, 1979·Archives of Oral Biology·V J Uitto, I Thesleff
Jan 1, 1981·British Journal of Plastic Surgery·A E Rintala, R Ranta
Mar 7, 2003·The Journal of Craniofacial Surgery·Francesco CarinciMauro Tognon

Citations

Mar 1, 1975·International Journal of Epidemiology·I Saxén
Aug 1, 1972·The Anatomical Record·G R Smiley, W E Koch
Oct 1, 1972·Plastic and Reconstructive Surgery·G R Smiley
Sep 22, 1971·Nature: New Biology·T F Paine, J Nagington
Nov 1, 1966·Acta paediatrica Scandinavica·K S Larsson, M Eriksson
Sep 10, 1971·Nature·M EisingerF K Sanders
Jul 5, 2007·Journal of Lipid Research·Barbara P AtshavesFriedhelm Schroeder

Related Concepts

Mice, Inbred CBA
Structure of Papilla Incisiva of Mouth
Zorprin
Maxillofacial Development
Mice, Inbred A
Cleft Palate
Sodium Salicylate

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