Prolonged migraine aura: new insights from a prospective diary-aided study

The Journal of Headache and Pain
Michele VianaCristina Tassorelli

Abstract

There is limited literature on prolonged aura (PA - defined as an aura including at least one symptom for > 1 h and < 7d), and there are no prospective studies. The aim of this study is to characterize prospectively the phenotype and prevalence of PA. Two hundred and twenty-four patients suffering from migraine with aura were recruited from the Headache Centers of Pavia and Trondheim. Patients prospectively described, on an ad hoc diary, each aura symptom (AS), the duration of AS and headache, and headache features. Seventy-two patients recorded three consecutive auras in their diaries. 19 (26.4%) of patients suffered at least one PA. Out of 216 recorded auras, 38 (17.6%) were PAs. We compared PAs with non-PAs with respect to 20 features; PAs were characterized by a higher number of non-visual symptoms (non-VS) (p < 0.001). No other differences were found. We obtained similar results when we compared auras with at least one symptom with a duration of > 2 h (n = 23) or > 4 h (n = 14) with the the others (n = 193 and n = 202 respectively). PAs are quite common. They do not differ from the other auras (even when their duration extends to 2 and/or 4 h) with the exception of a higher number of non-VS.

References

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Jul 15, 2015·Cephalalgia : an International Journal of Headache·Michele VianaCristina Tassorelli
Aug 31, 2016·Cephalalgia : an International Journal of Headache·Michele VianaCristina Tassorelli

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Citations

Feb 6, 2020·Antioxidants·Marta GoschorskaDariusz Chlubek
Mar 3, 2020·Stroke; a Journal of Cerebral Circulation·Emma A KoemansGisela M Terwindt
Aug 27, 2019·F1000Research·Robin M van Dongen, Joost Haan
Apr 5, 2019·The Journal of Headache and Pain·Nouchine Hadjikhani, Maurice Vincent
Aug 31, 2019·Headache·Dan Buch, Hugues Chabriat
May 21, 2020·Current Neurology and Neuroscience Reports·Joshua Lai, Esma Dilli
Apr 4, 2021·Children·Hannah F J Shapiro, Alyssa Lebel

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