Prolonged refractory status epilepticus with early and persistent restricted hippocampal signal MRI abnormality.

Journal of Neurology
Laurent ChevretViviane Bouilleret

Abstract

We report a series of four children with a prolonged refractory status epilepticus with an early persistent and restricted hippocampal signal MRI abnormality but otherwise no proven etiology. The mean duration of status epilepticus was 53 days (range, 20-91 days) with a mean length of stay in Pediatric Intensive Care Unit (PICU) of 2 months (range, 26-115 days). Neurological outcome showed epilepsy disease in all, and mild to severe disability. In long-term follow-up, the initial MRI signal abnormality developed into a cortical atrophy in all cases. The establishment of the diagnosis, etiology, and options for treatment are discussed.

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Citations

Mar 17, 2010·Epilepsy Currents·Thomas P Bleck
Oct 12, 2010·Brain & Development·Sarah Catharina GrünertKarl Otfried Schwab
Feb 26, 2016·Lancet Neurology·Francesc GrausJosep Dalmau
Jun 23, 2009·Epilepsy Research·Yen-Chu HuangJiann-Der Lee
Sep 7, 2016·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·F ChiusoloS Picardo
Jun 5, 2016·Multiple Sclerosis : Clinical and Laboratory Research·M CalabreseS Monaco
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Aug 15, 2018·Archives of Disease in Childhood·Petros Fessas, Amedine Duret
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Sep 30, 2017·Neurology. Neuroimmunology and Neuroinflammation·Takahiro IizukaKazutoshi Nishiyama
Jul 31, 2020·Neurology. Neuroimmunology and Neuroinflammation·Atsuko YanagidaTakahiro Iizuka
Nov 7, 2020·Seminars in Neurology·Tanya J W McDonald, Mackenzie C Cervenka
Jul 10, 2020·Biomedical Journal·Kuang-Lin LinHuei-Shyong Wang
Dec 15, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Michel MazzucaCatherine Chiron

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