PMID: 1211992Aug 1, 1975Paper

Prolonged secretion of lithogenic bile after cholecystectomy

Annals of Surgery
R M McDougallO G Thurston

Abstract

Hepatic bile samples were obtained from 8 subjects 1 1/2 to 23 years after cholecystectomy for presumed cholesterol gallstones. The content of cholesterol, bile acids and lecithin was determined for each bile sample and compared to the values found in gallbladder bile in 15 control subjects undergoing cholecystectomy for pure and mixed cholesterol stones. Plot of the data on triangular coordinates and subsequent determination of lithogenic index showed that bile was supersaturated with cholesterol in both groups of patients. The cholesterol content of bile remained at supersaturated levels following cholecystectomy and showed no tendency to return toward normal levels with the passage of time.

References

Feb 1, 1973·Analytical Biochemistry·R Engert, M D Turner
Feb 15, 1973·The New England Journal of Medicine·A L MetzgerS M Grundy
Jun 1, 1973·The Journal of Clinical Investigation·R T HolzbachK Holan
Dec 6, 1973·The New England Journal of Medicine·H R AlmondL Swell
Jan 6, 1972·The New England Journal of Medicine·R G DanzingerJ L Thistle
Jul 9, 1970·The New England Journal of Medicine·D M Small, S Rapo
May 1, 1968·The Journal of Clinical Investigation·W H Admirand, D M Small

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Citations

May 1, 1989·The Journal of Clinical Investigation·F BerrG Paumgartner
Aug 13, 2013·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Rena C MoonMuhammad A Jawad
Oct 1, 1976·The Journal of Surgical Research·R M McDougallO G Thurston
Jul 4, 2015·American Journal of Physiology. Gastrointestinal and Liver Physiology·Aditya J DesaiLaurence J Miller

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