Abstract
The aim of this study was to examine the impact of prolonged intensive care unit (ICU) stay on in-hospital mortality and long-term survival. Prospectively collected data from 6,101 consecutive patients who underwent surgery between 2003 and 2007 were analyzed. Prolonged ICU stay was defined as a total duration of ICU stay of 3 days or more postoperatively, including readmissions; patients with an ICU stay less than 3 days were identified as controls. Univariate and multiple variable analyses were performed to identify risk factors associated with prolonged ICU stay. Of 6,101 patients, 1,139 (18.7%) patients had a prolonged ICU stay. These patients had a higher ICU mortality (10%) compared with controls (0.6%; p < 0.001). On discharge from the ICU, their hospital mortality was still 6-fold higher (1.2%) compared with controls (0.2%; p < 0.001). Finally, the patients who had prolonged ICU stays had lower survival after discharge from the ICU-89.2% and 81.2% at 1 year and 3 years, respectively, compared with 97.8% and 93.6%, respectively, for controls (p < 0.001). Multiple variable analysis revealed prolonged ICU stay to be an independent predictor of prolonged hospital stay, higher hospital mortality, and poorer long-term surviva...Continue Reading
References
Jan 1, 1991·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·U S PrasadE W Cameron
Jun 1, 1997·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·R M WesselinkJ A Leusink
Oct 7, 1997·Circulation·C D WarnerR A Guyton
Oct 23, 1997·Chest·T A RyanN J Starr
Aug 4, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F RoquesL Thulin
Mar 18, 2000·Heart·D R LawrenceT Treasure
Nov 22, 2001·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·T S KurkiM Leijala
Jan 15, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Serban C StoicaSamer A M Nashef
Sep 25, 2003·Intensive Care Medicine·Jan BuceriusFriedrich W Mohr
Oct 31, 2003·European Heart Journal·Evgenij V PotapovRoland Hetzer
Jan 30, 2004·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Douglas P B JanssenRene M H J Brouwer
Sep 24, 2004·Transfusion·Ognjen GajicS Breanndan Moore
Dec 29, 2004·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Ioannis K ToumpoulisJoseph J DeRose
Feb 21, 2006·The Annals of Thoracic Surgery·Ortrud Vargas HeinClaudia Spies
Mar 2, 2006·Anesthesiology·Wei PanCharles D Collard
Mar 23, 2006·Asian Cardiovascular & Thoracic Annals·Lusine AbrahamyanHrair Hovaguimian
Jun 8, 2007·Critical Care : the Official Journal of the Critical Care Forum·Marya D ZilberbergAndrew F Shorr
Jan 8, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Joseph F DastaJohn A Kellum
Aug 20, 2008·Indian Journal of Medical Sciences·Saeed DavoodiSeyed Hesameddin Abbasi
Nov 26, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alain VuylstekeMartin Utley
Citations
May 3, 2014·Heart, Lung & Circulation·Cheng-Nan LiLi-Zhong Sun
Mar 19, 2015·Research in Cardiovascular Medicine·Rasoul AzarfarinAlireza Yaghoubi
Jul 24, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Andreas KosterJan F Gummert
Jan 19, 2016·The Nigerian Postgraduate Medical Journal·Babatunde Babasola OsinaikeOluyemisi Olusesin
Jun 28, 2012·The Annals of Thoracic Surgery·Jacob T Gutsche, Albert T Cheung
Jan 1, 2015·Critical Care : the Official Journal of the Critical Care Forum·F Shaun HoseinHenry T Stelfox
Jul 4, 2015·Medical Science Monitor Basic Research·Fabian DoerrKhosro Hekmat
Aug 9, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Pey-Jen YuAlan R Hartman
Nov 6, 2015·Journal of Cardiothoracic Surgery·Jia LiuSu Dong
Apr 4, 2014·The Annals of Thoracic Surgery·Albert T Cheung, W Andrew Kofke
Sep 22, 2017·Journal of Intensive Care Medicine·Ryosuke HiguchiShuichiro Takanashi
Nov 7, 2018·Critical Care Medicine·Vatsal TrivediBernard McDonald
Aug 26, 2020·Journal of Cardiac Surgery·Ursula F Mackie-Savage, Judith Lathlean
Mar 23, 2017·European Heart Journal·Qingping WuZhengyuan Xia
Aug 17, 2019·The Annals of Pharmacotherapy·Christopher J MichaudTomasz Timek
Aug 26, 2015·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Antonia KalogianniHero Brokalaki
Mar 14, 2020·Critical Care Explorations·Hannah L GaleSteven G Schauer
Feb 25, 2020·The Korean Journal of Thoracic and Cardiovascular Surgery·Dong Jung KimKay-Hyun Park
May 22, 2019·Frontiers in Physiology·Huilin WangKefang Guo
May 19, 2020·Zeitschrift für Gesundheitswissenschaften = Journal of public health·S MiuraS Kimura
Jul 6, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Carmelo DominiciMassimo Chello
Mar 2, 2021·The Journal of Thoracic and Cardiovascular Surgery·James A BrownIbrahim Sultan
Mar 23, 2021·Transfusion Medicine·Divyajot SadanaSudhir Krishnan
Feb 29, 2020·The Journal of Surgical Research·Fangyu ChenKarthik Raghunathan
May 26, 2021·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kai-Di KaoNai-Kuan Chou
Sep 3, 2021·BMC Health Services Research·Hao LiGang Li
Nov 6, 2021·Pediatric Transplantation·Aline MisarBarbara E Wildhaber