Prolonged stay in intensive care unit is a powerful predictor of adverse outcomes after cardiac operations

The Annals of Thoracic Surgery
Balakrishnan MaheshAlain Vuylsteke

Abstract

The aim of this study was to examine the impact of prolonged intensive care unit (ICU) stay on in-hospital mortality and long-term survival. Prospectively collected data from 6,101 consecutive patients who underwent surgery between 2003 and 2007 were analyzed. Prolonged ICU stay was defined as a total duration of ICU stay of 3 days or more postoperatively, including readmissions; patients with an ICU stay less than 3 days were identified as controls. Univariate and multiple variable analyses were performed to identify risk factors associated with prolonged ICU stay. Of 6,101 patients, 1,139 (18.7%) patients had a prolonged ICU stay. These patients had a higher ICU mortality (10%) compared with controls (0.6%; p < 0.001). On discharge from the ICU, their hospital mortality was still 6-fold higher (1.2%) compared with controls (0.2%; p < 0.001). Finally, the patients who had prolonged ICU stays had lower survival after discharge from the ICU-89.2% and 81.2% at 1 year and 3 years, respectively, compared with 97.8% and 93.6%, respectively, for controls (p < 0.001). Multiple variable analysis revealed prolonged ICU stay to be an independent predictor of prolonged hospital stay, higher hospital mortality, and poorer long-term surviva...Continue Reading

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Citations

Mar 19, 2015·Research in Cardiovascular Medicine·Rasoul AzarfarinAlireza Yaghoubi
Jul 24, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Andreas KosterJan F Gummert
Jan 19, 2016·The Nigerian Postgraduate Medical Journal·Babatunde Babasola OsinaikeOluyemisi Olusesin
Jun 28, 2012·The Annals of Thoracic Surgery·Jacob T Gutsche, Albert T Cheung
Jan 1, 2015·Critical Care : the Official Journal of the Critical Care Forum·F Shaun HoseinHenry T Stelfox
Jul 4, 2015·Medical Science Monitor Basic Research·Fabian DoerrKhosro Hekmat
Aug 9, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Pey-Jen YuAlan R Hartman
Apr 4, 2014·The Annals of Thoracic Surgery·Albert T Cheung, W Andrew Kofke
Sep 22, 2017·Journal of Intensive Care Medicine·Ryosuke HiguchiShuichiro Takanashi
Aug 26, 2020·Journal of Cardiac Surgery·Ursula F Mackie-Savage, Judith Lathlean
Aug 26, 2015·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Antonia KalogianniHero Brokalaki
May 19, 2020·Zeitschrift für Gesundheitswissenschaften = Journal of public health·S MiuraS Kimura
Mar 2, 2021·The Journal of Thoracic and Cardiovascular Surgery·James A BrownIbrahim Sultan
Feb 29, 2020·The Journal of Surgical Research·Fangyu ChenKarthik Raghunathan
May 26, 2021·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kai-Di KaoNai-Kuan Chou

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