Prolymphocytic leukemia of helper cell phenotype: report of a case and review of the scientific literature

American Journal of Clinical Pathology
W C ChanR K Brynes

Abstract

A case of prolymphocytic leukemia was studied by using light and electron microscopy, cytochemistry and multiple immunological markers for T and B lymphocytes. Cytochemical and immunological studies showed that the cells were T-lymphocytes. By using monoclonal antibodies to human T-cell subsets, we found that these cells had the T-helper cell phenotype. The usefulness of multiparameter studies in subclassifying T-cell malignancies is discussed and the literature on T-prolymphocytic leukemia reviewed.

Citations

Apr 13, 2000·Cancer Control : Journal of the Moffitt Cancer Center·E Matutes
Aug 1, 1984·Blut·W J PichlerW Drommer
Oct 1, 1985·American Journal of Hematology·J M JasonB L Evatt
Feb 1, 1985·Scandinavian Journal of Haematology·A BerrebiE Nir
Jan 20, 1983·The New England Journal of Medicine·J VieiraS H Landesman
Jan 1, 1984·Scandinavian Journal of Haematology. Supplementum·J M JasonR B Ramsey
Aug 15, 1987·Cancer·H C Kluin-NelemansA Brand

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