Promoter methylation in head and neck tumorigenesis.

Methods in Molecular Biology
Josena K StephenMaria J Worsham

Abstract

In addition to genetic alterations of gains and losses, epigenetic events of promoter methylation appear to further undermine a destabilized genomic repertoire in squamous head and neck carcinoma (HNSCC). This chapter provides an overview of frequently methylated tumor suppressor genes in benign head and neck papillomas, primary HNSCC tumors, and HNSCC cell lines and their relevance as epigenetic markers in head and neck tumorigenesis.

Citations

May 3, 2013·The Journal of Clinical Investigation·Efterpi KostareliJochen Hess
Dec 25, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jonathan M BernsteinJarrod J Homer
Dec 22, 2012·CA: a Cancer Journal for Clinicians·Dan P ZandbergKevin J Cullen

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