Promotion of Early Gut Colonization by Probiotic Intervention on Microbiota Diversity in Pregnant Sows

Frontiers in Microbiology
Katarina VeljovićAmarela Terzic-Vidojevic

Abstract

The aim of this work was to design a novel mixed probiotic culture for piglets and to evaluate its beneficial effect on the piglets' gut health. The possible mechanisms of probiotic activity, such as adhesion, competitive pathogen exclusion and influence on gut microbiota diversity were determined. Mixed probiotic starter culture is composed of three thermophilic lactic acid bacteria (LAB) strains: Lactobacillus helveticus BGRA43, Lactobacillus fermentum BGHI14 and Streptococcus thermophilus BGVLJ1-44. The strains BGVLJ1-44 and BGRA43 showed good technological properties (fast milk curdling, strong proteolytic activity). In addition, the strain BGVLJ1-44 produces exopolysaccharide (EPS), BGHI14 is heterofermentative LAB strain with significant immunomodulatory effect, while the strain BGRA43 showed strong antimicrobial activity against different pathogens and exhibited significantly higher level of adhesion to Caco-2 cells comparing to other two strains. Both lactobacilli strains BGRA43 and BGHI14 (p < 0.05), as well as probiotic combination (p < 0.01) significantly reduced the adhesion of Escherichia coli ATCC25922 to Caco-2 cells, while the strains BGVLJ1-44 (p < 0.01) and BGRA43 (p < 0.05) significantly reduced adhesion of S...Continue Reading

References

Dec 23, 1999·Research in Veterinary Science·S C KyriakisL Jansegers
Jun 27, 2001·Applied and Environmental Microbiology·R L van WinsenF van Knapen
Sep 30, 2004·International Journal of Food Microbiology·H M TimmermanA C Beynen
Jun 1, 1991·Applied and Environmental Microbiology·M KojicL Topisirovic
Jul 5, 2006·Environmental Microbiology·Sergey R KonstantinovWillem M de Vos
Dec 22, 2006·International Journal of Food Microbiology·Amarela Terzic-VidojevicLjubisa Topisirovic
Aug 28, 2007·Journal of Microbiological Methods·M Carmen ColladoSeppo Salminen
Jan 20, 2009·Current Drug Metabolism·Maria Carmen ColladoYolanda Sanz
Jul 29, 2010·Nature Reviews. Gastroenterology & Hepatology·Mélanie G GareauW Allan Walker
Mar 27, 2012·Animal : an International Journal of Animal Bioscience·M KennyB Miller
Jan 16, 2013·Therapeutic Advances in Gastroenterology·Peera Hemarajata, James Versalovic
Jan 25, 2013·Frontiers in Microbiology·Ivana StrahinicLjubisa Topisirovic
Jul 16, 2013·Applied and Environmental Microbiology·Jovanka LukicJelena Begovic
Aug 6, 2014·Antonie van Leeuwenhoek·Magdalena Polak-BereckaAnna Sroka-Bartnicka
May 21, 2015·ILAR Journal·Mei Wang, Sharon M Donovan
Nov 12, 2016·Microbial Pathogenesis·Emmanouil Angelakis
Feb 28, 2017·Protein and Peptide Letters·Shenglan HuZongyong Jiang
Jun 1, 1989·Revue Scientifique Et Technique·J Tournut

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Citations

Jan 9, 2019·Frontiers in Veterinary Science·Christine UnterwegerIsabel Hennig-Pauka
Feb 23, 2019·Frontiers in Microbiology·Jian ZhouYulong Yin
Jan 2, 2021·Frontiers in Bioengineering and Biotechnology·Karan AroraSatya Prakash
Jan 29, 2021·Animals : an Open Access Journal From MDPI·Laia BlaviJosé Francisco Pérez

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