Prompt-gamma compensation in Rb-82 myocardial perfusion 3D PET/CT.

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Fabio P EstevesJohn R Votaw

Abstract

To compare the diagnostic accuracy of Rb-82 myocardial perfusion three-dimensional (3D) PET with and without prompt-gamma compensation (PGC). Retrospective, single center study of 76 patients who had rest and adenosine stress Rb-82 myocardial perfusion 3D PET. All studies were acquired using a Siemens Biograph-40 PET/CT scanner and were reconstructed with and without PGC. Fifty-seven patients (mean age 63 +/- 11 years, 26 men) had coronary angiography within 40 days of Rb-82 imaging. Nineteen patients (mean age 43 +/- 7 years, 10 men) had low likelihood of coronary artery disease (CAD). All PET images were scored by consensus of two blinded readers on a standard 5-point scale using a 17-segment left ventricular model. A normal PET test was defined as a summed stress score of less than four. Obstructive CAD at coronary angiography was used as the gold-standard and was defined as luminal stenoses > or =50% in one or more major coronary arteries. The prevalence of obstructive disease at coronary angiography was 68% (39/57). The mean summed stress score was 12 +/- 12 for PGC images and was 18 +/- 14 for non-PGC images. Sensitivity and specificity for obstructive CAD were 90% (95% CI 88-99) and 72% (95% CI 52-93) for PGC images and ...Continue Reading

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Feb 14, 2012·Current Cardiology Reports·Piotr J SlomkaGuido Germano
Jul 3, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ran KleinRobert A deKemp
Sep 10, 2013·PloS One·Veronika PreylowskiMichael Lassmann
May 15, 2013·Imaging in Medicine·Ryo NakazatoPiotr Slomka
Jun 21, 2014·Seminars in Nuclear Medicine·Piotr J SlomkaGuido Germano
Apr 25, 2012·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Chietsugu KatohNagara Tamaki
Sep 22, 2012·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Tyler KasterRobert A deKemp
Nov 7, 2012·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Piotr J SlomkaGuido Germano
May 10, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jennifer M RenaudRobert A DeKemp
Jun 6, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R Glenn WellsTerrence D Ruddy
Jul 12, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ibrahim DanadPaul Knaapen
Jul 23, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·James A Case, Timothy M Bateman
Feb 6, 2016·European Journal of Nuclear Medicine and Molecular Imaging·Roberto SciagràUNKNOWN Cardiovascular Committee of the European Association of Nuclear Medicine (EANM)
Dec 22, 2015·Seminars in Nuclear Medicine·Piotr J SlomkaGuido Germano
Nov 23, 2015·Cardiology Clinics·Guido GermanoPiotr Slomka
May 15, 2015·IEEE Transactions on Medical Imaging·Jonathan B MoodyEdward P Ficaro
Feb 24, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Piotr J SlomkaDaniel Berman
Apr 15, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jonathan B MoodyVenkatesh L Murthy
Feb 28, 2015·Progress in Cardiovascular Diseases·Piotr J SlomkaGuido Germano
Oct 9, 2014·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·John J SunderlandYusuf Menda
Jul 31, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Piotr J SlomkaGuido Germano
Sep 15, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ian S ArmstrongParthiban Arumugam
Sep 24, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Valeria M Moncayo, Ernest V Garcia
Apr 10, 2015·Physics in Medicine and Biology·P E N BraadP F Høilund-Carlsen
Jul 8, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·David Karimeddini, Steven Bergmann
Jul 4, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Thomas RasmussenPhilip Hasbak
May 7, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Martin Lyngby LassenPiotr J Slomka
Jul 25, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Andrew Van ToshKenneth J Nichols
Jun 17, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Paul K R DasariMark F Smith
Nov 3, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Roberto SciagràUNKNOWN Cardiovascular Committee of the European Association of Nuclear Medicine (EANM)
May 14, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Liliana Arida-MoodyVenkatesh L Murthy
Nov 20, 2013·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Jennifer M RenaudRobert A deKemp

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