Prone position during ECMO is safe and improves oxygenation

The International Journal of Artificial Organs
Valesca KippingMaria Deja

Abstract

Combination of prone positioning (PrP) and extracorporeal membrane oxygenation (ECMO) might be beneficial in severe acute respiratory distress syndrome (ARDS), because both approaches are recommended. However, PrP during ECMO might be associated with complications such as dislocation of ECMO cannulae. We investigated complications and change of oxygenation effects of PrP during ECMO to identify "responders" and discuss our results considering different definitions of response in the literature. Retrospective analysis of complications, gas exchange, and invasiveness of mechanical ventilation during first and second PrP on ECMO at specified time points (before, during, and after PrP). We used multivariate nonparametric analysis of longitudinal data (MANOVA) to compare changes of mechanical ventilation and hemodynamics associated with the first and second procedures. In 12 ECMO patients, 74 PrPs were performed (median ECMO duration: 10 days (IQR: 6.3-
15.5 days)). No dislocations of intravascular catheters/cannulae, endotracheal tubes or chest tubes were observed. Two PrPs had to be interrupted (endotracheal tube obstruction, acute pulmonary embolism). PaO2/FiO2-ratio increased associated with the first and second PrP (p = 0.002) ...Continue Reading

Associated Clinical Trials

References

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Citations

Apr 29, 2016·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Victor van Berkel
Oct 30, 2016·Tuberculosis and Respiratory Diseases·Young-Jae ChoUNKNOWN Korean Academy of Tuberculosis and Respiratory Diseases Consensus Group
Sep 15, 2017·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Oliver JansenUwe Hamsen
Nov 30, 2016·Current Opinion in Critical Care·Onnen MoererMichael Quintel
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Mar 11, 2015·Intensive Care Medicine·Jonathan D MarhongEddy Fan
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Jul 10, 2020·Critical Care : the Official Journal of the Critical Care Forum·Jonathan RilingerTobias Wengenmayer
Aug 14, 2021·Critical Care : the Official Journal of the Critical Care Forum·Wynne Hsing PoonKiran Shekar
Dec 12, 2020·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Hanna ChaplinRachael Parke
Sep 1, 2021·Critical Care : the Official Journal of the Critical Care Forum·Oriol RocaMarina García-de-Acilu

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Methods Mentioned

BETA
sedation

Software Mentioned

SAS
SPSS
COPRA System

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