PRoNTo: pattern recognition for neuroimaging toolbox.

J SchrouffJ Mourão-Miranda


In the past years, mass univariate statistical analyses of neuroimaging data have been complemented by the use of multivariate pattern analyses, especially based on machine learning models. While these allow an increased sensitivity for the detection of spatially distributed effects compared to univariate techniques, they lack an established and accessible software framework. The goal of this work was to build a toolbox comprising all the necessary functionalities for multivariate analyses of neuroimaging data, based on machine learning models. The "Pattern Recognition for Neuroimaging Toolbox" (PRoNTo) is open-source, cross-platform, MATLAB-based and SPM compatible, therefore being suitable for both cognitive and clinical neuroscience research. In addition, it is designed to facilitate novel contributions from developers, aiming to improve the interaction between the neuroimaging and machine learning communities. Here, we introduce PRoNTo by presenting examples of possible research questions that can be addressed with the machine learning framework implemented in PRoNTo, and cannot be easily investigated with mass univariate statistical analysis.


Jun 22, 2000·NeuroImage·J Ashburner, K J Friston
Mar 30, 2005·Neural Networks : the Official Journal of the International Neural Network Society·Athanassia ChalimourdaAlex J Smola
Apr 15, 2005·Journal of Cognitive Neuroscience·Alice J O'TooleJames V Haxby
Apr 27, 2005·Nature Neuroscience·John-Dylan Haynes, Geraint Rees
Apr 27, 2005·Nature Neuroscience·Yukiyasu Kamitani, Frank Tong
May 24, 2005·NeuroImage·Stephen LaConteXiaoping Hu
Jun 16, 2005·NeuroImage·John Ashburner, Karl J Friston
Dec 24, 2005·Science·Sean M PolynKenneth A Norman
Mar 16, 2006·Proceedings of the National Academy of Sciences of the United States of America·Nikolaus KriegeskortePeter Bandettini
Jun 23, 2006·Nature Reviews. Neuroscience·John-Dylan Haynes, Geraint Rees
Jul 13, 2006·European Journal of Pharmacology·Barbara BorroniAlessandro Padovani
Feb 13, 2007·Current Biology : CB·John-Dylan HaynesRichard E Passingham
Jan 19, 2008·Brain : a Journal of Neurology·Stefan KlöppelRichard S J Frackowiak
Nov 8, 2008·Science·Elia FormisanoRainer Goebel
Dec 17, 2008·NeuroImage·Francisco PereiraMatthew Botvinick
Jan 17, 2009·NeuroImage·John Ashburner, Karl J Friston
Feb 3, 2009·Neuroinformatics·Michael HankeStefan Pollmann
Feb 13, 2009·Frontiers in Neuroinformatics·Michael HankeStefan Pollmann
Jan 15, 2010·NeuroImage·Katja FrankeUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Mar 17, 2010·Current Biology : CB·Martin J ChadwickEleanor A Maguire
Mar 30, 2010·NeuroImage·Carlton ChuJohn Ashburner
Jun 15, 2010·NeuroImage·Rémi CuingnetUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Oct 1, 2010·Medical Image Computing and Computer-assisted Intervention : MICCAI·Nikhil SinghSarang Joshi
Dec 22, 2010·NeuroImage·Steven LemmKlaus-Robert Müller
Jan 11, 2011·NeuroImage·John Ashburner, Karl J Friston
Nov 19, 2011·NeuroImage·Stefan KlöppelPrashanthi Vemuri

❮ Previous
Next ❯


Aug 13, 2013·PloS One·Erik ZieglerChristophe Phillips
Sep 10, 2013·Neuroinformatics·Benson MwangiJair C Soares
Mar 29, 2014·Neuroinformatics·Dominik GrotegerdUdo Dannlowski
Dec 23, 2015·Journal of Neuroscience Methods·Jessica SchrouffJosef Parvizi
Feb 18, 2016·NeuroImage·Marta GhioMarco Tettamanti
Oct 9, 2015·NeuroImage. Clinical·Christian LambertHugh S Markus
Jan 16, 2016·NeuroImage·Orlando FernandesJanaina Mourao-Miranda
Nov 6, 2015·Brain Connectivity·Mangor PedersenGraeme Jackson
Mar 5, 2016·Brain : a Journal of Neurology·Lorna HarperJonathan M Schott
Dec 23, 2015·BMC Neurology·Sanja NedicJaime S Ide
Aug 26, 2015·Human Brain Mapping·Lara SchlaffkeTobias Schmidt-Wilcke
Dec 8, 2015·Journal of Affective Disorders·Wenjing YangJiang Qiu
Nov 17, 2015·Social Neuroscience·Frank Van OverwalleKris Baetens
Mar 26, 2016·Frontiers in Computational Neuroscience·Qasim BukhariLino Becerra
Sep 21, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Peng FuLingge Wei
Oct 7, 2015·Frontiers in Human Neuroscience·Timothy L HodgsonIan R Summers
Jan 28, 2015·Annals of Neurology·James H ColeUNKNOWN Alzheimer's Disease Neuroimaging Initiative
May 21, 2013·NeuroImage·O M DoyleA F Marquand
Nov 19, 2013·Behavioural Brain Research·Andreas FrickTomas Furmark
Jun 6, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Martin WegrzynJohanna Kissler
May 6, 2016·Frontiers in Psychiatry·Rafael O'HalloranSophia Frangou
Apr 22, 2014·Journal of the American Academy of Child and Adolescent Psychiatry·Heledd HartKatya Rubia
Oct 13, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Chun-Ting HsuMarkus Conrad
Feb 28, 2015·Psychoneuroendocrinology·Elseline HoekzemaJulie Bakker
Jan 23, 2015·Frontiers in Neuroinformatics·Martin N HebartJohn-Dylan Haynes
Oct 14, 2014·Frontiers in Human Neuroscience·Benedikt SundermannBettina Pfleiderer
May 5, 2016·Journal of Neuroscience Methods·Sudhir RamanKlaas Enno Stephan
Aug 9, 2016·Frontiers in Neuroinformatics·Nikolaas N OosterhofJames V Haxby
Sep 24, 2016·Journal of Alzheimer's Disease : JAD·Miguel Ángel Araque CaballeroUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Nov 9, 2016·Proceedings of the National Academy of Sciences of the United States of America·Amy L DaitchJosef Parvizi

❮ Previous
Next ❯

Methods Mentioned

feature extraction

Software Mentioned

Matlab Python Python

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.