Propensity for adverse pregnancy outcomes in African-American women may be explained by low energy expenditure in early pregnancy

The American Journal of Clinical Nutrition
Jasper MostLeanne M Redman

Abstract

African-American (AA) women have poorer pregnancy outcomes, and studies in nonpregnant women suggest a different etiology of weight gain in AA compared with white women. We hypothesized that physiologic factors such as low energy expenditure and physical activity would be present in AA compared with white women in pregnancy. We aimed to identify physiologic risk factors for disordered energy balance in AA and white women early in pregnancy. This was a cross-sectional study in 66 pregnant women with obesity, between 14 and 16 wk of gestation. Energy intake was calculated using the intake-balance method. Energy expenditure was measured in free-living conditions [total daily energy expenditure (TDEE)] over 7 d with the use of doubly labelled water and during sleep [sleeping EE (SleepEE)] in a room calorimeter. Body composition was measured by air displacement plethysmography and physical activity by accelerometers. Markers of metabolic health were obtained from fasting blood and urine. AA (n = 34) and white (n = 32) women were comparable in age (mean ± SEM: 27.7 ± 0.6 y), enrollment body mass index [mean ± SEM (in kg/m2): 36.9 ± 0.7], and body fat (mean ± SEM: 45.0% ± 0.6%). AA women had more fat-free mass (P = 0.01) and tended to...Continue Reading

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Citations

Aug 2, 2019·The Journal of Clinical Investigation·Jasper MostLeanne M Redman
Aug 2, 2019·The American Journal of Clinical Nutrition·Jasper Most, Leanne M Redman
Aug 9, 2019·Nutrients·Jasper MostLeanne M Redman
May 7, 2019·Scandinavian Journal of Medicine & Science in Sports·Jasper MostLeanne M Redman

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