Properties and applications of microbial transglutaminase

Applied Microbiology and Biotechnology
K YokoyamaY Kikuchi


Some properties and applications of the transglutaminase (TGase) referred to as microbial TGase (MTGase), derived from a variant of Streptomyces mobaraensis (formerly classified as Streptoverticillium mobaraense), are described. MTGase cross-linked most food proteins, such as caseins, soybean globulins, gluten, actin, myosins, and egg proteins, as efficiently as mammalian TGases by forming an epsilon-(gamma-glutamyl)lysine bond. However, unlike many other TGases, MTGase is calcium-independent and has a relatively low molecular weight. Both of these properties are of advantage in industrial applications; a number of studies have illustrated the potential of MTGase in food processing and other areas. The crystal structure of MTGase has been solved. It provides basic structural information on the MTGase and accounts well for its characteristics. Moreover, an efficient method for producing extracellular MTGase has been established using Corynebacterium glutamicum. MTGase may be expected to find many uses in both food and non-food applications.


Jan 26, 2008·Applied Microbiology and Biotechnology·Hiroshi Itaya, Yoshimi Kikuchi
Sep 24, 2008·Applied Microbiology and Biotechnology·Yu-Jen YuMing-Te Yang
Nov 28, 2012·Applied Microbiology and Biotechnology·Tobias HeckLinda Thöny-Meyer
Apr 26, 2013·Applied Microbiology and Biotechnology·Maria T GundersenJoelle N Pelletier
May 27, 2008·Journal of Industrial Microbiology & Biotechnology·Shie-Jea LinWen-Shen Chu
May 5, 2007·Biotechnology Letters·Patricia K Carvajal-VallejosMireya Santos
Jun 8, 2007·Journal of Materials Science. Materials in Medicine·Y GarciaA Pandit
Jul 10, 2012·Journal of Materials Science. Materials in Medicine·Linda ElowssonBo Mattiasson
Jan 9, 2013·World Journal of Microbiology & Biotechnology·Hongbo LiShumei Wang
Jul 13, 2007·Applied Biochemistry and Biotechnology·James LangstonFeng Xu
May 4, 2013·Applied Biochemistry and Biotechnology·Marcela Pavan Bagagli, Hélia Harumi Sato
Jul 20, 2012·Journal of Agricultural and Food Chemistry·Chunqiang LiJie Chen
Jan 5, 2011·The Journal of Biological Chemistry·Ming-Te YangTienHsiung Thomas Li
Mar 11, 2011·Critical Reviews in Food Science and Nutrition·Raffaele PortaConcetta Valeria L Giosafatto
Jul 4, 2012·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·A KaufmannM Widmer
Dec 17, 2008·Applied and Environmental Microbiology·Yoshimi KikuchiLong-Fei Wu
May 8, 2010·The British Journal of Ophthalmology·David Y S ChauFelicity R A J Rose
Apr 22, 2008·PLoS Pathogens·Michael T Bethune, Chaitan Khosla
Jan 1, 2010·Biotechnology & Genetic Engineering Reviews·Dongxu ZhangJian Chen
Dec 24, 2013·Bioconjugate Chemistry·Santiago E FariasArvind Rajpal
Nov 8, 2013·Folia Microbiologica·Marek Kieliszek, Anna Misiewicz
Aug 18, 2012·Clinical & Developmental Immunology·Giuseppe MazzarellaMauro Rossi
Jun 7, 2014·Applied Microbiology and Biotechnology·Inge J MintenMarco A van den Berg
Jun 27, 2012·Functional & Integrative Genomics·C OsorioS Rustgi
Jun 21, 2014·Journal of Industrial Microbiology & Biotechnology·Yihan LiuFuping Lu
Jun 26, 2014·Applied Microbiology and Biotechnology·Ivone M MartinsAltino Branco Choupina
Aug 5, 2014·Meat Science·M D Romero de ÁvilaM I Cambero
Oct 14, 2014·Food Chemistry·Ana Luisa Camolezi Gaspar, Silvana Pedroso de Góes-Favoni
Nov 19, 2013·Applied and Environmental Microbiology·Kun DuZhemin Zhou
Feb 29, 2008·Digestive Diseases and Sciences·Maria Letizia FaliniFabio Forlani

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.