Properties and characteristics of a bacteriocin from Serratia marcescens.

Journal of Bacteriology
J D Foulds, D Shemin

Abstract

A strain of Serratia marcescens was found to produce a bacteriocin that inhibits the growth of certain Escherichia coli strains. This inhibition was bacteriocidal rather than bacteriostatic and was not caused by a bacteriophage. Whereas the bacteriocin was inactive on the 7 Serratia strains tested, it killed 11 of the 20 E. coli strains tested for sensitivity. A relationship of the bacteriocin to a possible colicin cannot as yet be excluded, although E. coli mutants resistant to 1 or 2 of 15 different colicins remained sensitive to the bacteriocin. The bacteriocidal effect by the bacteriocin could be interrupted in a substantial fraction of the treated cell population by the addition of trypsin. The synthesis of the bacteriocin was inducible by ultraviolet light or by starvation for thymidine. Both procedures led to a similar increase in maximum bacteriocin titer relative to noninduced cultures.

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Citations

Mar 9, 1999·Folia Microbiologica·J Smarda, D Smajs
Aug 26, 1998·FEMS Microbiology Letters·M J Benedik, U Strych
Jul 21, 2015·Critical Reviews in Food Science and Nutrition·Ramith RamuNagendra Prasad M N
Jul 19, 2019·Expert Review of Anti-infective Therapy·Luigi SantacroceLucrezia Bottalico
Sep 1, 1971·Journal of Bacteriology·J Foulds
May 1, 1971·Applied Microbiology·W H TraubT S Startsman
Jan 1, 1983·Journal of Clinical Microbiology·P S LaiC W Wang

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