Properties and potential medical applications of regenerated casein fibers crosslinked with citric acid

International Journal of Biological Macromolecules
Yiqi Yang, Narendra Reddy

Abstract

Regenerated protein fibers developed from casein using alkaline solutions and crosslinked with citric acid have good tensile properties and water stability but were cytotoxic. Casein is obtained as a byproduct during skim milk production but has limited industrial applications. In this research, casein was dissolved using alkaline solutions and the effects of fiber formation conditions on the tensile properties was studied before and after crosslinking with citric acid. Crosslinked casein fibers had tensile strength as high as 110 MPa and breaking elongation of 13.6%. The fibers were also stable in 90°C water between pH 3 and 9 but were hydrolyzed at pH 11. Casein was cytotoxic and did not support the attachment and growth of mouse fibroblasts.

References

Dec 1, 1969·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·G G GlennerE D Eanes
Feb 13, 2007·Biomacromolecules·Narendra Reddy, Yiqi Yang
Jun 26, 2007·Journal of Agricultural and Food Chemistry·Weijie XuYiqi Yang
Oct 31, 2007·Journal of Materials Science. Materials in Medicine·Narendra Reddy, Yiqi Yang
Feb 19, 2009·Biotechnology Progress·Narendra ReddyYiqi Yang
Jul 29, 2009·Biotechnology Progress·Narendra Reddy, Yiqi Yang
Mar 10, 2010·International Journal of Biological Macromolecules·Narendra Reddy, Yiqi Yang
Sep 2, 2010·International Journal of Biological Macromolecules·Pornanong AramwitTeerapol Srichana
Jun 15, 2011·Trends in Biotechnology·Narendra Reddy, Yiqi Yang

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Citations

Jan 22, 2020·Journal of the Science of Food and Agriculture·Miri Klein, Elena Poverenov

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