PMID: 42293Sep 1, 1979

Properties of influenzavirus nucleocapsids in nonpermissive cells

Acta Virologica
A G BukrinskayaT A Assadulaev


The properties of fowl plague virus (Influenzavirus A) nucleocapsids isolated from the cytoplasm of infected Ehrlich ascites carcinoma cells and chick embryo cells were compared. Nucleocapsids isolated from both systems possessed similar polypeptides (P and NP) but differed in their biophysical characteristics. Nucleocapsids from ascites cells sedimented in velocity sucrose gradients slower (from 25 to 50 S) and the majority of them banded at higher density in CsCl gradients (rho 1.38 as compared to 1.34 g/ml) than nucleocapsids from chick embryo cells. In the electron microscope they appeared as thin threads 3--4 nm in diameter.

Related Concepts

Carcinoma, Ehrlich Tumor
Centrifugation, Density Gradient
Chick Embryo
Electron Microscopy
Orthomyxovirus Type A, Porcine
Viral Proteins

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