PMID: 6980364May 29, 1982Paper

Properties of methicillin-resistant staphylococci now endemic in Australia

The Medical Journal of Australia
J Gedney, R W Lacey

Abstract

Seventy-eight cultures of multiresistant Staphylococcus aureus (MRSA), obtained from Australian hospitals in 1981, were studied to see whether they possessed novel properties responsible for their epidemic spread. In general, these strains resembled MRSA from other countries and were probably derived from them; in particular, they did not survive desiccation better than other staphylococci. The majority of MRSA produced lipases, which might be responsible for their invasiveness, and all produced high amounts of beta-lactamase which hydrolysed each of the isoxazolyl penicillins. This may account for therapeutic failure with cloxacillin of flucloxacillin. Control of this epidemic should rely principally on general measures against the hospital staphylococcus.

References

Oct 1, 1979·Journal of General Microbiology·R W Lacey, A Stokes
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Aug 1, 1972·Journal of Clinical Pathology·R W Lacey
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Citations

Aug 1, 1983·European Journal of Clinical Microbiology·C T Keane, M T Cafferkey
Aug 11, 2004·American Journal of Clinical Dermatology·Iain B Gosbell
Feb 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A SorianoE Soriano
Sep 6, 1986·British Medical Journal·J W DundeeA G Lynas
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·M T CafferkeyC T Keane
Jun 1, 1990·Journal of Paediatrics and Child Health·J Webster, J L Faoagali
Sep 15, 1984·The Medical Journal of Australia·D E TownsendW B Grubb
Jun 1, 1983·Antimicrobial Agents and Chemotherapy·B R LyonR A Skurray
Mar 1, 1987·Microbiological Reviews·B R Lyon, R Skurray

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