Abstract
Seventy-eight cultures of multiresistant Staphylococcus aureus (MRSA), obtained from Australian hospitals in 1981, were studied to see whether they possessed novel properties responsible for their epidemic spread. In general, these strains resembled MRSA from other countries and were probably derived from them; in particular, they did not survive desiccation better than other staphylococci. The majority of MRSA produced lipases, which might be responsible for their invasiveness, and all produced high amounts of beta-lactamase which hydrolysed each of the isoxazolyl penicillins. This may account for therapeutic failure with cloxacillin of flucloxacillin. Control of this epidemic should rely principally on general measures against the hospital staphylococcus.
References
Mar 29, 1979·Nature·S Phillips, R P Novick
Oct 1, 1979·Journal of General Microbiology·R W Lacey, A Stokes
Jan 1, 1977·Journal of Clinical Pathology·R W Lacey, A Stokes
Dec 1, 1965·Journal of General Microbiology·K Rosendal, P Bülow
Aug 1, 1972·Journal of Clinical Pathology·R W Lacey
Nov 1, 1973·Journal of Medical Microbiology·R W Lacey, J Grinsted
Apr 1, 1973·Journal of General Microbiology·J Grinsted, R W Lacey
Jun 11, 1971·Annals of the New York Academy of Sciences·P Bülow
Nov 7, 1981·Lancet·M I McDonaldA Sinclair
Nov 14, 1981·Lancet·M S SprottH R Ingham
Jun 1, 1981·The Journal of Antimicrobial Chemotherapy·H GiamarellouG K Daikos
Aug 22, 1981·The Medical Journal of Australia·M McDonaldK N Sim
Citations
Aug 1, 1983·European Journal of Clinical Microbiology·C T Keane, M T Cafferkey
Aug 11, 2004·American Journal of Clinical Dermatology·Iain B Gosbell
Feb 21, 2019·Antimicrobial Agents and Chemotherapy·Sarah L BainesTimothy P Stinear
Apr 1, 1986·The Journal of Hygiene·R R MarplesM J de Saxe
Sep 6, 1986·British Medical Journal·J R StephensonS Tabaqchali
Feb 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A SorianoE Soriano
Sep 6, 1986·British Medical Journal·J W DundeeA G Lynas
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·M T CafferkeyC T Keane
Jun 1, 1990·Journal of Paediatrics and Child Health·J Webster, J L Faoagali
Sep 15, 1984·The Medical Journal of Australia·D E TownsendW B Grubb
Jan 21, 1985·The Medical Journal of Australia·D E TownsendW B Grubb
Jun 1, 1983·Antimicrobial Agents and Chemotherapy·B R LyonR A Skurray
Mar 1, 1987·Microbiological Reviews·B R Lyon, R Skurray
May 29, 1998·The Journal of Hospital Infection·W el-Adhami, P Stewart