May 1, 1975

Properties of partially purified ATP desaminase from Actinomyces N4 antibioticus

Voprosy medit︠s︡inskoĭ khimii
L F Maksimova

Abstract

Three active fractions of ATP desaminase from Actinomyces N4 of type Antibioticus were obtained by gel filtration through Sephadex G-200. Some properties of each fraction were studied: effect of pH and Mg2+, substrate specificity, effect of pH on Km. The enzyme studied could be used for preparation of ITP, IDP, IMP, inosine and hypoxantine.

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Mentioned in this Paper

Actinomyces
Nucleotide Deaminases
Hydrogen-Ion Concentration
Adenosine Triphosphate, Chromium Ammonium Salt
Magnesium

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Actinomycosis is a rare, chronic, and slowly progressive granulomatous disease caused by filamentous Gram positive anaerobic bacteria from the Actinomycetaceae family (genus Actinomyces). The disease is characterised by the formation of painful abscesses in the mouth, lungs,breast or gastrointestinal tract. Discover the latest research on actinomycosis here.

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