Prophylactic antibiotics in the prevention of catheter-associated bloodstream bacterial infection in preterm neonates: a systematic review

Journal of Perinatology : Official Journal of the California Perinatal Association
A LodhaA M Moore

Abstract

To evaluate the efficacy of prophylactic antibiotics in preventing infection associated with central venous catheters in preterm neonates. The search strategy of the Cochrane Neonatal Review Group was used. The following databases were searched: Medline, Cochrane Central Register of Controlled Trials, CINAHL and EMBASE. In addition, we hand-searched abstracts of Pediatric Academic Societies annual meetings published in Pediatric Research (1990 to July 2007) and Canadian Pediatric Society annual meeting proceedings (1990 to July 2007). No language restrictions were applied. Included were randomized controlled trials of antibiotics given prophylactically to prevent infection in preterm infants (<37 completed weeks) less than 1-month old admitted to neonatal intensive care units. Both centrally or peripherally inserted central venous catheters were included. Assessment of methodological quality and extraction of data for included trials was undertaken independently by two authors. When suitable, data from trials were combined in a meta-analysis. A total of three studies were found which addressed the role of prophylactic antibiotics to prevent catheter-related infection in neonates. Two studies used vancomycin as the prophylactic ...Continue Reading

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Citations

Nov 26, 2010·The Pediatric Infectious Disease Journal·Walter ZinggDidier Pittet
Jan 5, 2011·Journal of Paediatrics and Child Health·Jinlin Wu, Dezhi Mu
Mar 15, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·P PanagiotounakouA K Gounaris
Jul 31, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Jacqueline E TaylorKenneth Tan
May 18, 2010·Neonatal Network : NN·Marie Corzine, Lynne D Willett
Apr 6, 2017·BMC Pediatrics·Gary AlcockPeter H Gray
Nov 15, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Matthew F NiednerMarlene R Miller
Oct 26, 2013·American Journal of Physiology. Gastrointestinal and Liver Physiology·Michael L JensenPer T Sangild
Dec 19, 2015·American Journal of Physiology. Gastrointestinal and Liver Physiology·Malene M BirckThomas Thymann
Feb 28, 2015·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Michelle A HoffmanAnn L Anderson-Berry
Jul 15, 2015·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Gail E ReynoldsJonathan M Klein
Jan 3, 2021·Pediatrics·Michael L RinkeSuzette O Oyeku

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