Prophylactic central neck dissection and local recurrence in papillary thyroid microcarcinoma: a meta-analysis

Brazilian Journal of Otorhinolaryngology
Hui Su, Yujie Li

Abstract

For papillary thyroid microcarcinoma patients, the reported incidence of lymph node metastasis is as high as 40%, and these occur mainly in the central compartment of the neck. Because these metastases are difficult to detect using ultrasonography preoperatively, some authors advocate routine central neck dissection in papillary thyroid microcarcinoma patients at the time of initial thyroidectomy. To evaluate whether prophylactic central neck dissection can decrease the local recurrence rate of papillary thyroid microcarcinoma after thyroidectomy. The publicly available literature published from January 1990 to December 2017 concerning thyroidectomy plus prophylactic central neck dissection versus thyroidectomy for papillary thyroid microcarcinoma was retrieved by searching the national and international online databases. A meta-analysis was performed after the data extraction process. Four studies were finally included with a total of 727 patients, of whom, 366 cases underwent thyroidectomy plus prophylactic central neck dissection and 361 cases received thyroidectomy only. As shown by the meta-analysis results, the recurrence rates in cases of thyroidectomy plus prophylactic central neck dissection were approximately 1.91% an...Continue Reading

Citations

May 6, 2020·World Journal of Clinical Cases·Xin WuXiao-Dong He
Nov 16, 2020·Current Oncology Reports·Panagiotis AsimakopoulosAlfio Ferlito
Nov 2, 2020·Cancer Treatment and Research Communications·Associate Professor And Senior Advisor Dr Debashish MukherjeeAssociate Professor And Senior Advisor Dr Naresh Saidha
Apr 11, 2021·American Journal of Otolaryngology·Ahmet DirikocBekir Cakir
Oct 29, 2021·The Laryngoscope·Khaled M AlsubaieAmeen Z Alherabi

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