Jan 1, 1980

Prophylactic lignocaine and early post-coronary artery occlusion dysrhythmias in anaesthetized greyhounds

British Journal of Pharmacology
R J Marshall, J R Parratt

Abstract

1. Lignocaine (1 mg kg-1 min-1 infused intravenously for 30 min) greatly reduced the incidence of ventricular ectopic beats that resulted from acute coronary artery ligation in anaesthetized greyhound dogs. However, the incidence of ventricular fibrillation was only slightly reduced by this treatment which caused significant myocardial depression. 2. There is no good evidence from this study that lignocaine is a particularly effective prophylactic in acute myocardial infarction.

Mentioned in this Paper

Ventricular Fibrillation
Myocardial Dysfunction
Greyhound
Coronary Occlusion
Myocardial Infarction
Entire Coronary Artery
Anesthesia Procedures
Cardiomyopathies
Sinus Node Artery
Coronary Artery

About this Paper

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.