Jan 1, 1980

Prophylactic lignocaine and early post-coronary artery occlusion dysrhythmias in anaesthetized greyhounds

British Journal of Pharmacology
R J Marshall, J R Parratt


1. Lignocaine (1 mg kg-1 min-1 infused intravenously for 30 min) greatly reduced the incidence of ventricular ectopic beats that resulted from acute coronary artery ligation in anaesthetized greyhound dogs. However, the incidence of ventricular fibrillation was only slightly reduced by this treatment which caused significant myocardial depression. 2. There is no good evidence from this study that lignocaine is a particularly effective prophylactic in acute myocardial infarction.

Mentioned in this Paper

Ventricular Fibrillation
Myocardial Dysfunction
Coronary Occlusion
Myocardial Infarction
Entire Coronary Artery
Anesthesia Procedures
Sinus Node Artery
Coronary Artery

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