Prophylactic Phosphate Supplementation for the Inpatient Treatment of Restrictive Eating Disorders

The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine
Maya LeitnerHolly Agostino

Abstract

The medical stabilization of adolescent patients with restrictive eating disorders can be associated with refeeding syndrome, a potentially fatal complication preceded by refeeding hypophosphatemia (RH). Whether RH can be prevented by routine prophylactic phosphate supplementation has not been previously examined. This study sought to determine the safety and efficacy of a refeeding strategy that incorporates prophylactic phosphate supplementation to prevent RH. Retrospective chart data were collected for patients aged younger than 18 years with restrictive eating disorders admitted to a tertiary pediatric inpatient ward between January 2011 and December 2014. All patients were refed with a standardized protocol that included prophylactic oral phosphate supplementation (1.0 ± .2 mmol/kg/day). During the 4-year study period, 75 admissions (70 patients) were included for analysis. The mean age and percent median body mass index of included patients were 15.3 years and 83.5%, respectively. Seven out of 75 (9%) had percent median body mass index of <70% and 26 out of 75 (35%) had percent body weight loss >20%. All patients were normophosphatemic at the time of admission (mean serum phosphate 1.24 ± .2 mmol/L). Serial laboratory eva...Continue Reading

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Citations

May 18, 2016·Italian Journal of Pediatrics·Maria Rosaria MarchiliAlberto Villani
May 24, 2016·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Mark L Norris
Aug 22, 2017·Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie·Katharina BührenManuel Föcker
Jul 20, 2019·Journal of Clinical Medicine·Cristina CuerdaLoredana Arhip
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Nov 30, 2018·European Journal of Pediatrics·Anne BargiacchiJuliane Leger
Oct 15, 2021·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Donna GallagherRena Zelig

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