Prophylactic salpingectomy for prevention of ovarian cancer at the time of elective laparoscopic cholecystectomy

The British Journal of Surgery
G TomaschK Tamussino

Abstract

Most serous ovarian cancers are now understood to originate in the fallopian tubes. Removing the tubes (salpingectomy) likely reduces the risk of developing high-grade serous ovarian cancer. Numerous gynaecological societies now recommend prophylactic (or opportunistic) salpingectomy at the time of gynaecological surgery in appropriate women, and this is widely done. Salpingectomy at the time of non-gynaecological surgery has not been explored and may present an opportunity for primary prevention of ovarian cancer. This study investigated whether prophylactic salpingectomy with the intention of reducing the risk of developing ovarian cancer would be accepted and could be accomplished at the time of elective laparoscopic cholecystectomy. Women aged at least 45 years scheduled for elective laparoscopic cholecystectomy were recruited. They were counselled and offered prophylactic bilateral salpingectomy at the time of cholecystectomy. Outcome measures were rate of accomplishment of salpingectomy, time and procedural steps needed for salpingectomy, and complications. A total of 105 patients were included in the study. The rate of acceptance of salpingectomy was approximately 60 per cent. Salpingectomy was performed in 98 of 105 lap...Continue Reading

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Citations

Jan 9, 2021·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Henrik FalconerDaniel Altman
Mar 27, 2021·Seminars in Cancer Biology·Khalid El BairiSaid Afqir
Aug 26, 2021·International Journal of Colorectal Disease·Richard van der MeerRudi Roumen
Sep 19, 2021·American Journal of Obstetrics and Gynecology·Laura A M van LieshoutRosella P M G Hermens

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Methods Mentioned

BETA
hysterectomy

Clinical Trials Mentioned

NCT03171467

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