Prophylactic strategies before solid-organ transplantation

Current Opinion in Infectious Diseases
R K Avery

Abstract

Prophylactic measures prior to organ transplantation are evolving based on recent reports of emerging infectious diseases, as well as an expanded understanding of the epidemiology of familiar infections. This review will highlight developments with potential impact on donor and recipient screening and pretransplant management. Key findings regarding bacterial infections include the lack of utility of mupirocin intranasal decolonization for prevention of Staphylococcus aureus infections after liver transplantation, and the description of transmission of Pseudomonas infection to multiple recipients via an innominate artery graft. The implications of donor bacterial colonization in lung transplantation are further explored. The emergence of non-Candida albicans yeast and non-Aspergillus mold infections may lead to changes in prophylactic strategies. The majority of cystic fibrosis patients have had Aspergillus colonization at some time before transplant; one-quarter of these develop tracheobronchial aspergillosis and anastomotic complications. There are several key developments regarding viral infections. Donor-derived human herpesvirus-8-infected neoplastic cells have been identified in recipients with Kaposi sarcoma. The transmi...Continue Reading

References

Feb 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·N SinghI R Marino
Oct 6, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·F L Delmonico
Apr 20, 2002·Transplantation·Rajiv D PoduvalMichelle A Josephson
Dec 10, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robin K Avery
Apr 15, 2003·Nature Medicine·Patrizia BarozziGiuseppe Torelli
May 30, 2003·The New England Journal of Medicine·Martha IwamotoUNKNOWN West Nile Virus in Transplant Recipients Investigation Team
Jun 11, 2003·Chest·Samuel Z Goldhaber
Jul 24, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·J J Zarranz ImirizalduJ M Corral Carranceja
Jul 29, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·James R Burton, Thomas A Shaw-Stiffel
Sep 23, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Vassilios S AvlonitisJohn H Dark
Oct 2, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Fabrizio GinevriPatrizia Comoli
Jan 16, 2004·Transplantation·Emilio RamosRavinder K Wali

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Citations

Dec 21, 2007·The New England Journal of Medicine·Jay A Fishman
Apr 16, 2014·Current Opinion in Pediatrics·Carol Conrad, David N Cornfield
Jun 2, 2012·TheScientificWorldJournal·Jovana CukuranovicVladisav Stefanovic
Oct 14, 2006·Therapeutic Drug Monitoring·Irina BuhaescuAdrian Covic
Oct 23, 2010·Revue des maladies respiratoires·J-P GangneuxB Philippe
Jul 10, 2007·Seminars in Nephrology·Jay A Fishman
Mar 8, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S A FischerUNKNOWN AST Infectious Diseases Community of Practice
Jan 28, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S A FischerUNKNOWN AST Infectious Disease Community of Practice
Mar 6, 2010·Journal of Zhejiang University. Science. B·Lea Atanasova, Irina S Druzhinina
Jul 26, 2006·Respiration; International Review of Thoracic Diseases·Demet KarnakAtul C Mehta
Dec 20, 2005·International Immunology·Bock LimAndrew M Lew

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