PMID: 11906442Mar 22, 2002Paper

Prophylactic surgery to reduce breast cancer risk: a brief literature review

The Breast Journal
B O Anderson

Abstract

Prophylactic mastectomy reduces the likelihood of developing breast cancer among women at heightened risk for breast cancer, but at significant personal cost. Women at increased breast cancer risk on the basis of hormonal history, family history and/or genetic mutation carrier status may consider bilateral prophylactic mastectomy with or without reconstruction to reduce their cancer risk and/or decrease their chances of cancer mortality. Women having received mastectomy as treatment for breast cancer may request contralateral mastectomy to decrease the chances of developing a second breast primary. The potential oncologic value of these procedures must be weighed carefully on a case-by-case basis against the operation's physical and psychological morbidity. The purpose of this literature review is to provide a practice-oriented summary of recent clinical studies attempting to address the relative risks and benefits of preventive surgery for breast cancer. Data are included regarding the psychological factors surrounding patient selection and quality of life outcomes, which become the cornerstone of patient satisfaction and acceptance. Taken together, these data support the Society of Surgical Oncology position statement regardi...Continue Reading

References

Jul 1, 1984·Journal of Surgical Oncology·J E GoodnightD L Morton
Nov 1, 1984·American Journal of Surgery·S EldarJ D Beatty
Jan 1, 1997·Clinical Oncology : a Journal of the Royal College of Radiologists·M B JamesonG D Braatvedt
Apr 1, 1997·Annals of Surgical Oncology·T J YeatmanC E Cox
Aug 1, 1997·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K L CheungI O Ellis
Mar 21, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·V R GrannA I Neugut
Jan 14, 1999·The New England Journal of Medicine·L C HartmannR B Jenkins
Sep 2, 1999·Journal of the National Cancer Institute·T R RebbeckB L Weber
Sep 10, 1999·Preventive Medicine·M StefanekC Lerman
Sep 24, 1999·Annals of Surgical Oncology·L L MontgomeryP I Borgen
Nov 11, 1999·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J KolliasR W Blamey
Feb 9, 2000·JAMA : the Journal of the American Medical Association·D SchragJ C Weeks
Apr 13, 2000·Annals of Surgical Oncology·D K PayneM J Massie
Apr 28, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A EisenB L Weber
Jun 1, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B MeiserK Tucker
Jun 30, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·U JosephsonK Sandelin
Jul 13, 2000·JAMA : the Journal of the American Medical Association·M H FrostL C Hartmann
Jul 21, 2000·CA: a Cancer Journal for Clinicians·V G Vogel
Sep 16, 2000·Journal of the American College of Surgeons·L A NewmanS E Singletary
Jul 21, 2001·The New England Journal of Medicine·H Meijers-HeijboerJ G Klijn

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Citations

Aug 17, 2010·Breast Cancer Research and Treatment·Belén Merck
Nov 11, 2009·Journal of Genetic Counseling·Deborah J MacDonaldBetty Ferrell
Jun 7, 2003·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Joel ErblichDana H Bovbjerg
Mar 5, 2011·Annals of Surgery·Tari A KingMonica Morrow
Mar 8, 2007·BMC Women's Health·Mary McCullumLynda G Balneaves
Dec 6, 2008·Surgical Oncology Clinics of North America·Victoria Sahadevan FosslandScott H Kurtzman
Apr 23, 2014·Health Care for Women International·Lydia Aziato, Joe Nat A Clegg-Lamptey
Apr 6, 2018·The Cochrane Database of Systematic Reviews·Nora E CarbineHenry Ko
Nov 12, 2010·The Cochrane Database of Systematic Reviews·Liz LostumboJudi Wallace
Sep 25, 2004·Cancer·Katja GoldflamFunda Meric-Bernstam

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