PMID: 7426509Jul 1, 1980

Prophylaxis for Mendelson's syndrome before elective caesarean section. A comparison of cimetidine and magnesium trisilicate mixture regimens

British Journal of Obstetrics and Gynaecology
R P Husemeyer, H T Davenport

Abstract

A clinical trial was conducted in which patients undergoing elective Caesarean section received eitherrr oral cimetidine 400 mg or magnesium trisilicate mixture BPC 20 ml before anaesthesia. The pH values of gastric fluid were significantly higher and the incidence of pH less than 2.5 was significantly lower in patients who received magnesium trisilicate mixture BPC. No adverse effects were observed in newborn infants whose mothers had received cimetidine and there was no significant difference in pH values of gastric fluid from the newborn in the two groups. The findings suggest that as a means of prophylaxis for Mendelson's syndrome in patients undergoing elective Caesarean section, magnesium trisilicate mixture BPC 20 ml is more effective than a single oral dose of cimetidine 400 mg, administered in the manner described.

References

Oct 1, 1978·Anaesthesia·R P HusemeyerT Rajasekaran
Nov 1, 1976·British Journal of Anaesthesia·W D WhiteG H Stanley-Jones
May 1, 1975·British Journal of Anaesthesia·G Taylor
Oct 27, 1979·British Medical Journal·M J DenhamD A Tyrrell
Jan 1, 1977·British Journal of Anaesthesia·J S Crawford
May 1, 1977·British Journal of Anaesthesia·J D HoldsworthR G Roulston
Mar 15, 1976·American Journal of Obstetrics and Gynecology·R B Roberts, M A Shirley
Sep 1, 1971·British Journal of Anaesthesia·J S Crawford
Jan 1, 1970·The Journal of Obstetrics and Gynaecology of the British Commonwealth·J S DavisonD M Hay
Nov 25, 1965·The New England Journal of Medicine·L D Vandam
Feb 1, 1958·The Journal of Obstetrics and Gynaecology of the British Empire·J N HUNT, F A MURRAY
Mar 1, 1962·Anesthesiology·W K BANNISTER, A J SATTILARO
Aug 1, 1946·American Journal of Obstetrics and Gynecology·C L MENDELSON

Citations

Sep 1, 1982·Klinische Wochenschrift·G FeifelH Eissner
May 1, 1983·Canadian Anaesthetists' Society Journal·J G Williams
Mar 15, 2011·International Journal of Obstetric Anesthesia·Shantini ParanjothyJane Thomas
Jun 1, 1981·Anaesthesia·J S Crawford
Jan 1, 1982·Anaesthesia·J R JohnstonJ W Dundee
Sep 14, 2012·The Cochrane Database of Systematic Reviews·James D GriffithsJane Thomas
Oct 7, 1998·The Australian & New Zealand Journal of Obstetrics & Gynaecology·W Phuapradit
Feb 6, 2014·The Cochrane Database of Systematic Reviews·Shantini ParanjothyJane Thomas
Mar 1, 1989·DICP : the Annals of Pharmacotherapy·E R Gonzalez, S K Kallar
May 1, 1984·Drug Intelligence & Clinical Pharmacy·S F Kowalsky

Related Concepts

General Anesthesia
Paracervical Block
Antacids
Postcesarean Section
Tagamet
Gastric Acidity Determination
Guanidines
Magnesium
Aspiration Pneumonia

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