PMID: 15374152Nov 1, 1996Paper

Prophylaxis of thromboembolic events in congestive heart failure

Archives of Gerontology and Geriatrics
Giuseppe Di PasqualeG Pinelli

Abstract

In patients with heart failure the incidence of thromboembolism is 0.9-5.5%/year (mean 1.9%/year), but no randomized studies are available to support the indication for anticoagulant therapy in those patients. Atrial fibrillation and previous thromboembolic events seem to be the major risk factors, whereas the effect of ventricular dysfunction has not been independently evaluated; nonetheless several studies suggest that thromboembolism is more likely among those patients with lower ejection fraction and lower peak exercise oxygen consumption. Anticoagulant therapy seems to be indicated also in patients with left ventricular aneurysm with mobile and protruding thrombi. Several studies of patients with dilated cardiomyopathy show that the incidence of thromboembolism ranges from 1.6 to 4.5%/year in patients not treated with anticoagulants, while it is virtually absent in anticoagulated patients. The clinical opportunity of long-term anticoagulant treatment in heart failure patients should be weighted not only on the clinical markers of thromboembolic risk, but also on the relative risk/benefit ratio of the single patient.

References

Oct 1, 1977·The American Journal of Cardiology·R C HintonC M Fisher
Sep 1, 1978·Current Problems in Cardiology·J P SegalW P Harvey
Jul 1, 1989·Medical Decision Making : an International Journal of the Society for Medical Decision Making·J TsevatS G Pauker
Sep 1, 1985·Journal of the American College of Cardiology·A C LapeyreV Fuster
Mar 1, 1981·The American Journal of Cardiology·V FusterR L Frye
Aug 1, 1995·Stroke; a Journal of Cerebral Circulation·R G HartD C Anderson
Nov 23, 1994·JAMA : the Journal of the American Medical Association·D W Baker, R F Wright
Feb 1, 1993·European Heart Journal·S M JafriS Goldstein

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Citations

Oct 5, 2010·Artificial Organs·Daniel TimmsUlrich Steinseifer
Mar 9, 2021·Oxidative Medicine and Cellular Longevity·Shuang Ling, Jin-Wen Xu

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