PMID: 8969393Dec 1, 1996Paper

Propofol-alfentanil versus fentanyl-midazolam in coronary artery surgery

Journal of Cardiothoracic and Vascular Anesthesia
E CollardK Joucken

Abstract

To compare intraoperative hemodynamics profiles and recovery characteristics of propofol-alfentanil with fentanyl-midazolam anesthesia in elective coronary artery surgery. Prospective, randomized study. University hospital. Fifty patients with impaired or good left ventricular function. In group 1, (n = 25) anesthesia was induced with an infusion of propofol, 3 to 4 mg/kg/h, alfentanil, 500 micrograms, and pancuronium 0.1 mg/kg, and maintained with propofol, 3 to 6 mg/kg/h (variable rate), and alfentanil infusions, 30 micrograms/kg/h (fixed rate). Additional boluses of alfentanil, 1 mg, were administered before noxious stimuli; group 2 (n = 25) received a loading dose of fentanyl, 25 micrograms/kg, midazolam, 1.5 to 3 mg, and pancuronium, 0.1 mg/kg for induction, followed by an infusion of fentanyl, 7 micrograms/kg/h, for maintenance. Additional boluses of midazolam (1.5 to 3 mg) and fentanyl (250 micrograms) were administered before noxious stimuli. MEASUREMENTS AND MAIN RESULTS. Cardiovascular parameters at eight intraoperative time points as well as time to extubation, morphine consumption, and pain scores were recorded. Induction of anesthesia was associated in both groups with a small but significant decrease in mean arter...Continue Reading

References

Nov 1, 1977·Critical Care Medicine·P L KlinebergS J Aukburg
May 1, 1979·Canadian Anaesthetists' Society Journal·T H StanleyC H Coggins
Sep 1, 1977·Anesthesia and Analgesia·O PrakashW Hekman
Mar 1, 1975·Anesthesiology·G W OstheimerE Lowenstein
Apr 1, 1992·Anesthesiology·B RiouP Viars
Apr 1, 1992·The Annals of Thoracic Surgery·Y A LouagieJ C Schoevaerdts
Jun 1, 1992·Anesthesia and Analgesia·M MuziT J Ebert
Jul 1, 1990·Anesthesiology·D M PhilbinM N D'Ambra
Aug 1, 1990·British Journal of Anaesthesia·F BoerJ van der Krogt
Jul 1, 1989·British Journal of Anaesthesia·C S Goodchild, J M Serrao
Nov 1, 1969·Anesthesia and Analgesia·A H Goldberg, C H Padget
Dec 1, 1984·Acta Anaesthesiologica Scandinavica·H HeikkiläV Laaksonen
Aug 1, 1983·Critical Care Medicine·P R LichtenthalB A Shapiro
Aug 1, 1982·Acta Anaesthesiologica Scandinavica·P S SebelN Rog
Dec 1, 1980·Anesthesia and Analgesia·N MummaneniA Montoya
Aug 1, 1995·Journal of Cardiothoracic and Vascular Anesthesia·P M RoekaertsS de Lange
Aug 1, 1994·Anesthesiology·T YamanoueF G Estafanous
Apr 1, 1993·Journal of Cardiothoracic and Vascular Anesthesia·B A Shapiro, P R Lichtenthal

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Citations

Mar 29, 2013·International Journal of Health Care Quality Assurance·Juha-Matti LehtonenTeemu Moilanen
Oct 6, 2006·Expert Opinion on Pharmacotherapy·Robert MacLaren, Patrick W Sullivan
Jun 25, 2020·Journal of Cardiac Surgery·Sri Rama Ananta Nagabhushanam PadalaAjay Kumar Jha

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