PMID: 9641806Jun 26, 1998Paper

Propofol anesthesia, seizure duration, and ECT: a case report and literature review

The Journal of ECT
B A MartinS V Parikh

Abstract

Propofol is a nonbarbiturate anesthetic induction agent known to have anti-convulsant properties. When used as an anesthetic for electroconvulsive therapy (ECT), it can reduce seizure duration to a significant degree, which may not be fully appreciated. A case is presented in which propofol caused a 63.1% reduction in mean seizure duration compared with preceding and subsequent treatments with thiopental anesthesia. The literature on the use of propofol for ECT was reviewed with specific reference to its effect on seizure duration and any evidence of superiority to the barbiturate induction agents. It is concluded that propofol may have only very circumscribed indications as an anesthetic for ECT. If used, psychiatrists and anesthetists must be aware of its potency as an anticonvulsant.

Citations

May 14, 2010·International Urology and Nephrology·Cuneyd Ozkurkcugil, Levend Ozkan
Apr 11, 2001·Journal of Neurosurgical Anesthesiology·B WalderM R Tramèr
Jun 27, 2000·The Journal of ECT·W Chanpattana
Apr 2, 2002·The Journal of ECT·Cornelis StadtlandNikolaus Michael
Oct 24, 2002·The Journal of ECT·Catherine DattoStanley N Caroff
Jul 17, 2008·The Journal of ECT·W Michael Hooten, Keith G Rasmussen

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