Propofol-based anesthesia as compared with standard anesthetic techniques for middle ear surgery

Journal of Clinical Anesthesia
W S JellishS Fowles

Abstract

To determine if a total intravenous (i.v.) technique with propofol and fentanyl is superior to isoflurane anesthesia in patients undergoing middle ear surgery. Prospective, randomized study. Inpatient otolaryngology service at a university medical center. 102 ASA status I and II nonobese patients with no significant history of diabetes, chronic cholecystitis, neuropathy, or neuromuscular disorders that could produce delayed gastric emptying. Patients were admitted to the study and randomly divided into three equal groups. I.V. administration of thiopental sodium 5 mg/kg for induction of anesthesia followed by 60% air/oxygen (O2) with isoflurane 1% to 2% end-tidal for maintenance anesthesia (group 1). The same anesthetic was given as above, with the addition of droperidol 25 mcg/kg given after induction (group 2). I.V. administration of propofol 2 mg/kg for induction of anesthesia followed by propofol 50 to 250 mcg/kg/min for maintenance anesthesia. All groups received fentanyl 3 mcg/kg i.v. after induction. Surgical duration, induction, maintenance, and total anesthesia times were recorded in addition to eye opening and extubation. Intergroup comparisons of postoperative nausea, vomiting, and pain were done, as were recovery sc...Continue Reading

References

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Citations

Jun 30, 2000·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·I HenziM R Tramèr
Dec 7, 2007·Intensive Care Medicine·Nam Q NguyenRichard H Holloway
Jun 1, 2008·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Aziz Ul HaqRana Altaf Ahmed
May 30, 2006·Anesthesiology·Timothy E MoreyDonn M Dennis
Nov 11, 1998·Acta Anaesthesiologica Scandinavica·P Honkavaara, I Pyykkö
Sep 21, 2010·Anesthesiology Clinics·Sharon Liang, Michael G Irwin
Sep 18, 2016·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Marita WindpassingerDaniel I Sessler
Aug 10, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·W Scott JellishJohn P Leonetti
Oct 20, 2020·The Cochrane Database of Systematic Reviews·Stephanie WeibelPeter Kranke

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