Propofol for gastrointestinal endoscopy

United European Gastroenterology Journal
Toshihiro Nishizawa, Hidekazu Suzuki

Abstract

Most gastrointestinal endoscopic procedures are now performed with sedation. Moderate sedation using benzodiazepines and opioids continues to be widely used, but propofol sedation is becoming more popular because its unique pharmacokinetic properties make endoscopy almost painless, with a very predictable and rapid recovery process. There is controversy as to whether propofol should be administered only by anesthesia professionals. According to published values, endoscopist-directed propofol has a lower mortality rate than endoscopist-delivered benzodiazepines and opioids, and a comparable rate to general anesthesia by anesthesiologists. Rapid recovery has a major impact on patient satisfaction, post-procedure education and the general flow of the endoscopy unit. According to estimates, the absolute economic benefit of endoscopist-directed propofol implementation in a screening setting is probably substantial, with 10-year savings of $3.2 billion in the USA. Guidelines concerning the use of propofol emphasize the need for adequate training and certification in sedation by non-anesthetists.

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Citations

May 15, 2019·Current Opinion in Anaesthesiology·Julie Kuzhively, Jaideep J Pandit
Oct 29, 2019·Current Cancer Drug Targets·Milad AshrafizadehSaeed Samarghandian
Jul 7, 2020·Current Opinion in Anaesthesiology·Claudia Fernandez-Robles, Adriana D Oprea
Dec 17, 2019·World Journal of Gastrointestinal Endoscopy·Aureo Augusto de Almeida DelgadoEduardo Guimarães Hourneaux de Moura
Feb 1, 2020·Journal of Clinical Biochemistry and Nutrition·Toshihiro NishizawaOsamu Toyoshima
Oct 23, 2020·Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences·Hamidreza ShetabiDariush Moradi Farsani
Mar 17, 2021·Clinical Endoscopy·Toshihiro NishizawaKazuhiko Koike

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Methods Mentioned

BETA
sedation
dissection

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