Proposal for cervical cancer screening in the era of HPV vaccination

Obstetrics & Gynecology Science
Yung-Taek Ouh, Jae Kwan Lee

Abstract

Eradication of cervical cancer involves the expansion of human papillomavirus (HPV) vaccine coverage and the development of efficient screening guidelines that take vaccination into account. In Korea, the HPV National Immunization Program was launched in 2016 and is expected to shift the prevalence of HPV genotypes in the country, among other effects. The experiences of another countries that implement national immunization programs should be applied to Korea. If HPV vaccines spread nationwide with broader coverage, after a few decades, cervical intraepithelial lesions or invasive cancer should become a rare disease, leading to a predictable decrease in the positive predictive value of cervical screening cytology. HPV testing is the primary screening tool for cervical cancer and has replaced traditional cytology-based guidelines. The current screening strategy in Korea does not differentiate women who have received complete vaccination from those who are unvaccinated. However, in the post-vaccination era, newly revised policies will be needed. We also discuss on how to increase the vaccination rate in adolescence.

References

Apr 6, 2006·International Journal of Cancer. Journal International Du Cancer·Jack CuzickThomas Iftner
Feb 24, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·H S LeeH S Choi
May 15, 2007·The New England Journal of Medicine·UNKNOWN FUTURE II Study Group
May 17, 2008·American Journal of Epidemiology·Jill KoshiolJennifer S Smith
Aug 13, 2008·The Journal of Infectious Diseases·Laura K SycuroLaura A Koutsky
Sep 12, 2008·The Lancet Oncology·Francesca CarozziUNKNOWN New Technologies for Cervival Cancer Screening (NTCC) Working Group
Sep 12, 2008·International Journal of Cancer. Journal International Du Cancer·Jae Kwan JunKeun-Young Yoo
Nov 1, 2008·International Journal of Cancer. Journal International Du Cancer·Chris J L M MeijerPeter J F Snijders
Jul 30, 2009·BMJ : British Medical Journal·Philip E CastleUNKNOWN Proyecto Epidemiológico Guanacaste (PEG) Group
Nov 12, 2009·Journal of the National Cancer Institute·Maarit LeinonenAhti Anttila
Jan 22, 2010·The Lancet Oncology·Guglielmo RoncoUNKNOWN New Technologies for Cervical Cancer screening (NTCC) Working Group
Oct 19, 2010·The Lancet Oncology·Silvia de SanjoseUNKNOWN Retrospective International Survey and HPV Time Trends Study Group
Jun 21, 2011·Best Practice & Research. Clinical Obstetrics & Gynaecology·Maribel AlmonteJack Cuzick
Aug 6, 2011·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Nathalie GarçonMarcelle Van Mechelen
Sep 16, 2011·American Journal of Clinical Pathology·Thomas C WrightUNKNOWN ATHENA (Addressing THE Need for Advanced HPV Diagnostics) Study Group
Jun 8, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Nicolas WentzensenMark Schiffman
Jun 20, 2012·Annals of Internal Medicine·Virginia A Moyer, UNKNOWN U.S. Preventive Services Task Force
Dec 5, 2012·Vaccine·David FormanSilvia Franceschi
Jul 24, 2013·Cancer Prevention Research·Fang-Hui ZhaoPhilip E Castle
Oct 2, 2013·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·James DickinsonVerna Mai
Oct 5, 2013·The Journal of Infectious Diseases·Rebecca Howell-JonesGwenda Hughes
Oct 28, 2014·International Journal of Cancer. Journal International Du Cancer·Margot H UijterwaalChris J L M Meijer
Jan 18, 2015·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Emiko Y PetroskyEileen F Dunne
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Feb 19, 2015·The New England Journal of Medicine·Elmar A JouraUNKNOWN Broad Spectrum HPV Vaccine Study
Apr 29, 2015·Human Vaccines & Immunotherapeutics·Alain LuxembourgJoshua Chen
Jun 14, 2015·The Lancet Oncology·Aimée R KreimerUNKNOWN GSK Vaccines Clinical Study Support Group
Jul 23, 2015·Journal of Gynecologic Oncology·Kyung Jin MinJae Kwan Lee

❮ Previous
Next ❯

Citations

Jan 9, 2020·Artificial Cells, Nanomedicine, and Biotechnology·Yingrui FanRong Li
Oct 31, 2020·Analytical Cellular Pathology (Amsterdam)·Leilei XuXiaoping Liu
Dec 29, 2020·Obstetrics & Gynecology Science·Shahnaz GhalavandiReza Beiranvand
Apr 8, 2021·Journal of Gynecologic Oncology·Hyun Woong ChoJae Kwan Lee
Mar 20, 2019·Acta Cytologica·Andrea D OlivasRicardo R Lastra

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsies

Clinical Trials Mentioned

NCT00543543

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.