Proposed definition of the vaginal cuff and paracolpium clinical target volume in postoperative uterine cervical cancer

Practical Radiation Oncology
Naoya MurakamiJun Itami

Abstract

The aim of this study was to develop an appropriate definition for vaginal cuff and paracolpium clinical target volume (CTV) for postoperative intensity modulated radiation therapy in patients with uterine cervical cancer. A working subgroup was organized within the Radiation Therapy Study Group of the Japan Clinical Oncology Group to develop a definition for the postoperative vaginal cuff and paracolpium CTV in December 2013. The group consisted of 5 radiation oncologists who specialized in gynecologic oncology and a gynecologic oncologist. A comprehensive literature review that included anatomy, surgery, and imaging fields was performed and was followed by multiple discreet face-to-face discussions and e-mail messages before a final consensus was reached. Definitions for the landmark structures in all directions that demarcate the vaginal cuff and paracolpium CTV were decided by consensus agreement of the working group. A table was created that showed boundary structures of the vaginal cuff and paracolpium CTV in each direction. A definition of the postoperative cervical cancer vaginal cuff and paracolpium CTV was developed. It is expected that this definition guideline will serve as a template for future radiation therapy cl...Continue Reading

References

Dec 1, 1988·Baillière's Clinical Obstetrics and Gynaecology·W LichteneggerG Ralph
Jan 1, 1995·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·H Fritsch, H Hötzinger
Apr 14, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W A PetersD S Alberts
May 12, 2001·American Journal of Obstetrics and Gynecology·R TunnE E Quint
Nov 9, 2002·Anatomical Science International·Tomoyasu KatoYoshihiko Yabuki
Mar 3, 2004·Obstetrics and Gynecology·Wolfgang H UmekJohn O L DeLancey
Apr 18, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Vincent GrégoirePeter Levendag
Jun 15, 2006·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A E Bharucha
Jan 2, 2009·International Journal of Radiation Oncology, Biology, Physics·Robert J MyersonLisa A Kachnic
Apr 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Jeff M MichalskiCynthia Ménard
Feb 6, 2010·Japanese Journal of Clinical Oncology·UNKNOWN Japan Clinical Oncology GroupMasahiro Hiraoka
Feb 23, 2010·AJR. American Journal of Roentgenology·Nan ChenChun Yan Lu
Nov 26, 2010·International Journal of Radiation Oncology, Biology, Physics·Anuja JhingranPatricia J Eifel
Dec 17, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ina M Jürgenliemk-SchulzUulke A van der Heide
Jun 7, 2011·International Journal of Radiation Oncology, Biology, Physics·Eleanor E R HarrisKenneth Forster
Aug 31, 2011·Japanese Journal of Clinical Oncology·Takafumi ToitaUNKNOWN JCOG Radiation Therapy Study Group
Oct 18, 2011·World Journal of Urology·H FritschP Riss
Feb 3, 2012·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ivan ToledanoMichel Lapeyre
Feb 15, 2012·International Journal of Radiation Oncology, Biology, Physics·Michael J ZelefskyMargie Hunt
May 24, 2012·International Urogynecology Journal·Rajeev RamanahJohn O L DeLancey
Mar 19, 2013·Gynecologic Oncology·Jason D WrightDawn L Hershman

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