PMID: 9421799Jan 9, 1998Paper

Proposed link between Helicobacter pylori and sudden infant death syndrome

Medical Hypotheses
C P Pattison, B J Marshall

Abstract

Helicobacter pylori may be linked to sudden infant death syndrome (SIDS) through synthesis of inflammatory cytokines, particularly interleukin-1, which can produce fever, activation of the immune system, and increased deep sleep. A relatively minor respiratory or enteric infection, together with overwrapping and prone sleep position could then induce terminal hypoxemia. Alternatively, H. pylori produces large amounts of urease which, if aspirated in gastric juice, could reach the alveolae, react with plasma urea, and produce ammonia toxicity leading to respiratory arrest. Epidemiological similarities between H. pylori and SIDS are presented along with possible transmission mechanisms for H. pylori which support this hypothesis.

References

Feb 1, 1992·Archives of Disease in Childhood·R GilbertJ A Evans
Apr 1, 1990·Archives of Disease in Childhood·A C Engelberts, G A de Jonge
Feb 8, 1990·The New England Journal of Medicine·B DrummP M Sherman
Aug 1, 1994·FEMS Immunology and Medical Microbiology·C C BlackwellD A Mackenzie
Sep 15, 1994·Early Human Development·R WigfieldP J Fleming

❮ Previous
Next ❯

Citations

Mar 11, 2005·International Journal of Legal Medicine·Brigitte LoddenkötterThomas Bajanowski
Sep 12, 2000·Current Gastroenterology Reports·V Tolia
Oct 21, 2000·Archives of Disease in Childhood·J R KerrJ P Burnie
Mar 10, 1999·Journal of Clinical Pathology·J R Kerr
Feb 24, 2001·Lancet·M Rowland, B Drumm
Jun 12, 2001·Medical Hypotheses·E D Weinberg
Aug 25, 2004·FEMS Immunology and Medical Microbiology·Ashild Vege, Torleiv Ole Rognum
Jul 10, 2012·Experimental and Molecular Pathology·Valentina CasaleAnna Maria Lavezzi
Jun 18, 2003·The American Journal of Gastroenterology·F DubosC Carpentier
Jul 4, 2002·The American Journal of Gastroenterology·Yoram Elitsur
Jan 5, 2002·The American Journal of Gastroenterology·G Y HoB J Marshall
Mar 10, 1999·Journal of Clinical Pathology·T M Reynolds
Mar 10, 1999·Journal of Clinical Pathology·E O Olapade-OlaopaF K Habib

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.