Proprioception from a neurally controlled lower-extremity prosthesis

Science Translational Medicine
Tyler R ClitesHugh Herr

Abstract

Humans can precisely sense the position, speed, and torque of their body parts. This sense is known as proprioception and is essential to human motor control. Although there have been many attempts to create human-mechatronic interactions, there is still no robust, repeatable methodology to reflect proprioceptive information from a synthetic device onto the nervous system. To address this shortcoming, we present an agonist-antagonist myoneural interface (AMI). The AMI is composed of (i) a surgical construct made up of two muscle-tendons-an agonist and an antagonist-surgically connected in series so that contraction of one muscle stretches the other and (ii) a bidirectional efferent-afferent neural control architecture. The AMI preserves the dynamic muscle relationships that exist within native anatomy, thereby allowing proprioceptive signals from mechanoreceptors within both muscles to be communicated to the central nervous system. We surgically constructed two AMIs within the residual limb of a subject with a transtibial amputation. Each AMI sends control signals to one joint of a two-degree-of-freedom ankle-foot prosthesis and provides proprioceptive information pertaining to the movement of that joint. The AMI subject displa...Continue Reading

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Citations

Oct 4, 2019·Science Translational Medicine·Francesco Maria PetriniStanisa Raspopovic
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