Proprioceptive feedback determines visuomotor gain in Drosophila

Royal Society Open Science
Jan Bartussek, F O Lehmann

Abstract

Multisensory integration is a prerequisite for effective locomotor control in most animals. Especially, the impressive aerial performance of insects relies on rapid and precise integration of multiple sensory modalities that provide feedback on different time scales. In flies, continuous visual signalling from the compound eyes is fused with phasic proprioceptive feedback to ensure precise neural activation of wing steering muscles (WSM) within narrow temporal phase bands of the stroke cycle. This phase-locked activation relies on mechanoreceptors distributed over wings and gyroscopic halteres. Here we investigate visual steering performance of tethered flying fruit flies with reduced haltere and wing feedback signalling. Using a flight simulator, we evaluated visual object fixation behaviour, optomotor altitude control and saccadic escape reflexes. The behavioural assays show an antagonistic effect of wing and haltere signalling on visuomotor gain during flight. Compared with controls, suppression of haltere feedback attenuates while suppression of wing feedback enhances the animal's wing steering range. Our results suggest that the generation of motor commands owing to visual perception is dynamically controlled by propriocep...Continue Reading

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Citations

Aug 17, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Michael H Dickinson, Florian T Muijres
Apr 8, 2017·The Journal of Experimental Biology·Shwetha MureliJessica L Fox
Nov 18, 2018·The Journal of Experimental Biology·Mehmet F KeleşMark A Frye
Sep 15, 2017·Proceedings. Biological Sciences·Brandon PrattThomas Daniel
Dec 13, 2016·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Fritz-Olaf Lehmann, Jan Bartussek
Dec 23, 2016·Open Biology·E Axel GorostizaBjörn Brembs
Aug 31, 2018·Journal of the Royal Society, Interface·Jan Bartussek, Fritz-Olaf Lehmann
Dec 17, 2020·Proceedings. Biological Sciences·Bradley H Dickerson
Jan 28, 2021·Proceedings. Biological Sciences·Michael J Rauscher, Jessica L Fox
May 20, 2021·Physical Review. E·Alexander R SprengerHartmut Löwen
Oct 2, 2021·Journal of Physics. Condensed Matter : an Institute of Physics Journal·G H Philipp NguyenHartmut Löwen

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Methods Mentioned

BETA
fluorescence imaging

Software Mentioned

Matlab
MathWorks
Origin

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