PMID: 9170572Nov 1, 1996Paper

Pros-Eight transurethral radiofrequency thermotherapy for benign prostatic hyperplasia: preliminary clinical results

International Journal of Urology : Official Journal of the Japanese Urological Association
O YoshidaY Arai

Abstract

We have developed a new transurethral thermotherapy device using 8MHz radiofrequency (RF) for the treatment of patients with symptomatic benign prostatic hyperplasia (BPH). We report the safety and effectiveness of the initial clinical experience with this device. Sixty patients with symptomatic BPH were subjected to a single 1-hour treatment under local anesthesia. The treatment device uses extracorporeal RF capacitive heating in combination with radiative heating and conductive cooling of the urethra. In the 49 patients evaluable at 3 months, the mean International Prostate Symptom Score decreased from 17.8 to 13.1 (P < 0.0001) and the Quality of Life score decreased from 4.4 to 3.4 (P < 0.0005). Maximum flow rate increased from 8.1 to 9.7 mL/s (P < 0.05) at 3 months. Overall effectiveness by Homma's response criteria was as follows; excellent 4.1%, good 10.2%, fair 38.8% and poor 46.9%. Side effects were minimal. Gross hematuria was seen in 3 patients and erosion of the external urethral meatus was seen in 2 patients, but none had urinary retention. In this initial clinical trial, transurethral RF thermotherapy was safe and resulted in modest symptomatic improvement. Further investigations for optimizing the treatment protoc...Continue Reading

References

Aug 1, 1995·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Y C ParkH Kiwamoto
Jan 1, 1994·World Journal of Urology·J J de la RosetteS S Carter
Mar 1, 1995·International Journal of Urology : Official Journal of the Japanese Urological Association·Y HommaY Aso
Sep 1, 1995·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·A TeraiO Yoshida
Jan 1, 1993·European Urology·M DevonecS St Clair Carter
Jul 1, 1995·International Journal of Urology : Official Journal of the Japanese Urological Association·A TeraiO Yoshida
Jul 1, 1996·International Journal of Urology : Official Journal of the Japanese Urological Association·Y HommaY Ohashi

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